Polyphenol Extraction from White Grape Residue

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Solution Overview

Problem

Current methods for extracting polyphenols from white grape by-products are complex, require filtration steps, and are not easily scalable, limiting their industrial application and efficiency.

Innovation Solution

A simple method involving a mixture of white grape by-products and a dispersant, such as sand, with a solvent, followed by elution and recirculation of eluates, which avoids suspended solids and allows for the production of antioxidant and antibacterial extracts without the need for filtration, and can be scaled up for industrial use.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If conventional extraction methods are used to obtain polyphenols from white grape by-products, then polyphenol extraction can be achieved, but the process becomes complex and requires filtration steps

Engineering Contradiction:
Improvepolyphenol extraction efficiencyVSAvoidprocess complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The invention extracts and removes the problematic component (suspended solids) from the extraction process by using a filtration step, thereby simplifying the overall process while maintaining polyphenol extraction efficiency. The filtration step separates the desired polyphenol extract from solid particulates that would otherwise complicate the process.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The invention changes the extraction parameters by using specific solvent compositions (ethanol-water or methanol-water mixtures) and controlling extraction conditions to achieve efficient polyphenol extraction without generating excessive suspended solids, thereby reducing the need for complex filtration steps.

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If conventional extraction methods are used to obtain polyphenols from white grape by-products, then polyphenol extraction can be achieved, but the method is not easily scalable

Engineering Contradiction:
Improvepolyphenol extraction efficiencyVSAvoidscalability
Core Design Contradiction:
Quantity of substanceVSProductivity

Solution Approach 1:

The invention divides the extraction process into distinct, manageable stages (extraction, filtration, concentration) that can be independently optimized and scaled. This segmentation allows each step to be scaled up for industrial production while maintaining overall extraction efficiency and quality control.

Inventive Principle:
Principle #1Segmentation

3Reliability

If filtration steps are included in the extraction process, then suspended solids are removed, but the process becomes more complex and time-consuming

Engineering Contradiction:
Improveextract purityVSAvoidprocess steps
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The invention performs preliminary filtration or settling steps before the main extraction process to remove suspended solids in advance. This preliminary action prevents solids from interfering with the extraction and eliminates the need for complex post-extraction filtration, thereby maintaining extract purity while simplifying the overall process.

Inventive Principle:
Principle #10Preliminary action

4Quantity of substance

If more solvent is used in the extraction process, then polyphenol extraction efficiency increases, but solvent consumption and cost increase

Engineering Contradiction:
Improvepolyphenol extraction yieldVSAvoidsolvent consumption
Core Design Contradiction:
Quantity of substanceVSLoss of substance

Solution Approach 1:

The invention implements continuous extraction processes or multiple sequential extraction steps with the same solvent system, allowing the solvent to be reused or recycled. This continuity maintains high extraction efficiency while reducing overall solvent consumption compared to single-step extraction requiring large solvent volumes.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The invention recovers and reuses the extraction solvent after the extraction process through evaporation or distillation steps. The solvent is recovered from the polyphenol extract and reused in subsequent extraction cycles, thereby maintaining extraction efficiency while significantly reducing solvent consumption and cost.

Inventive Principle:
Principle #34Discarding and recovering

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method effectively extracts polyphenols with antioxidant and antibacterial properties, achieving high yields and reducing solvent consumption, and the resulting extracts are stable and suitable for cosmetic, pharmaceutical, and nutritional applications.

Implementation Method 1

preparing a mixture comprising a white grape by-product and a dispersant

Methodology Applied
Scientific EffectDispersion: Dispersion (of waves)

Implementation Method 2

adding a solvent, preferably an aqueous alcohol or an aqueous glycol

Methodology Applied
Scientific EffectSolvation: Solvation

Implementation Method 3

eluting, and collecting the eluates

Methodology Applied
Scientific EffectElution: Liquid-Liquid Extraction

Data Source

PatentEP2875822B1Polyphenol extract from white-grape residue
Publication Date: 2022.11.02 UNIVERSITY OF SANTIAGO DE COMPOSTELA
  • EP2875822B1 patent drawingFigure 1~2
  • EP2875822B1 patent drawingFigure 3
  • EP2875822B1 patent drawingFigure 4

AI summary

The invention relates to a polyphenol extract from white-grape residue. The invention relates to a straightforward method with few steps for obtaining extracts having antioxidant and anti-bacterial properties from white-grape residue. Due to the characteristics white-wine production, which is carried out by exclusively fermenting the must squeezed from the grapes, without any contact with the remains of pulp, skin and seeds, the residue generated during the method (white-grape bagasse) is very rich in polyphenols, since smaller amounts of same are transferred to the wine. The proposed procedure uses non-contaminating materials, takes place under gentle conditions and prevents the obtained eluates from containing suspended solids, enabling extracts rich in bioactive polyphenols to be obtained, which can be used on an industrial scale, essentially in the cosmetic, pharmaceutical and/or food industries.