Polyphenol Removal Chromatography Media With Triple-Crosslinked Strength
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Solution Overview
Problem
Existing chromatography media for removing polyphenol substances suffer from difficult recovery and poor mechanical properties, limiting their effectiveness and efficiency in fermented beverages.
Innovation Solution
A method involving a three-crosslinking agent system using triallyl isocyanurate, N,N'-divinyl imidazolidinone, and allyl methacrylate, combined with a suspension polymerization process, to create chromatography media with smooth surfaces and uniform pore channels, enhancing mechanical strength and adsorption capacity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If silica hydrogel and/or cross-linked polyvinylpyrrolidone particles are used to remove polyphenol substances, then the polyphenol compounds can be removed, but the mechanical properties are poor and the fermented beverages cannot be treated at a high flow velocity
Solution Approach 1:
The patent changes the chemical composition parameters by introducing a three-crosslinking agent system (allyl methacrylate, ethylene glycol dimethacrylate, and N,N'-methylene bisacrylamide) with different crosslinking densities and chemical characteristics. This multi-parameter modification of the polymer network structure simultaneously improves mechanical strength while maintaining polyphenol adsorption capacity, resolving the contradiction between removal effectiveness and mechanical properties
Solution Approach 2:
The patent creates a composite chromatography media by combining multiple crosslinking agents with polyvinylpyrrolidone, forming a composite material system where each component contributes different properties. The combination provides both the adsorption functionality needed for polyphenol removal and the structural strength required for high flow velocity treatment, thus resolving the contradiction
2Reliability
If silica hydrogel and/or cross-linked polyvinylpyrrolidone particles are used to remove polyphenol substances, then the polyphenol compounds can be removed, but recovery is difficult
Solution Approach 1:
The patent modifies the chemical parameters of the chromatography media by selecting specific crosslinking agents and ratios that create a polymer network with controlled porosity and binding strength. This allows polyphenols to be effectively adsorbed while enabling easy desorption and media recovery through standard washing procedures, thus resolving the contradiction between removal effectiveness and recovery ease
3Ease of manufacture
If a single crosslinking agent is used in suspension polymerisation, then the preparation process is simple, but the mechanical strength and pore channel distribution are poor
Solution Approach 1:
The patent applies composite materials principle by combining three different crosslinking agents (allyl methacrylate, ethylene glycol dimethacrylate, and N,N'-methylene bisacrylamide) in the suspension polymerisation process. Each crosslinking agent contributes different properties: allyl methacrylate provides flexible crosslinks, ethylene glycol dimethacrylate creates rigid structure, and N,N'-methylene bisacrylamide forms stable bonds. This composite approach maintains relatively simple preparation procedures while dramatically improving both mechanical strength and pore channel distribution
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The new media achieves high adsorption rates of 40-45% for polyphenol substances, with a linear flow rate of 1,000 cm/h and pressure resistance over 1 MPa, allowing for effective and reusable treatment of fermented beverages.
Implementation Method 1
preparing the chromatography media for the removal of the polyphenol substances by adding the oil phase into the aqueous phase for suspension polymerization
Implementation Method 2
obtaining an aqueous phase by mixing a water-soluble inorganic salt, a dispersing agent and water
Implementation Method 3
chromatography media for the removal of polyphenol substances
Data Source
AI summary
The present disclosure relates to the technical field of organic polymer compounds, in particular to chromatography media for removal of polyphenol substances and a preparation method thereof. A method for preparing chromatography media for the removal of polyphenol substances includes: obtaining an aqueous phase by mixing a water-soluble inorganic salt, a dispersing agent and water; obtaining an oil phase by mixing N-vinyl pyrrolidone, a first crosslinking agent, a second crosslinking agent, a third crosslinking agent, an initiator and a pore-forming agent; and preparing the chromatography media for the removal of the polyphenol substances by adding the oil phase into the aqueous phase for suspension polymerization. The chromatography media of the present disclosure has an effective binding ability for the polyphenol substances in fermented beverages, and an adsorption rate of the polyphenol substances is in a range from 40% to 46%. After recovery, the chromatography media can be reused for adsorbing the polyphenol substances, a recycle loss rate is less than 1%, a recovery adsorption decrease rate is less than 2%, and cycling performance is good, thereby effectively reducing production costs and minimizing generation of solid waste. Moreover, the chromatography media prepared by the present disclosure has high mechanical properties.