Fruit and Vegetable Pomace for Blood Glucose Modulation
Solution Overview
Problem
Current approaches fail to effectively prevent and manage type 2 diabetes and metabolic syndrome through dietary means, with a need for nutritional compositions and methods that can modulate carbohydrate uptake and metabolism.
Innovation Solution
The use of fruit or vegetable pomace, rich in a mixture of soluble and insoluble dietary fibers, is administered to alter carbohydrate uptake in the gastrointestinal system, thereby preventing, controlling, or treating diseases related to carbohydrate digestion and absorption.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional dietary approaches are used to manage type 2 diabetes, then blood glucose control is difficult to achieve, but pharmaceutical interventions have side effects and require medical supervision
Solution Approach 1:
The patent uses fruit and vegetable pomace as an intermediary substance between diet and blood glucose control. The pomace contains dietary fibers that act as a mediator to slow carbohydrate absorption in the gastrointestinal tract, providing glucose control without the direct pharmacological effects and side effects of drugs like metformin or acarbose.
Solution Approach 2:
The patent changes the physical and chemical parameters of the dietary fiber in pomace through processing methods (drying, grinding to specific particle sizes of 50-200 mesh) to optimize its blood glucose modulating effects. The fiber content is standardized at 30-60% by weight, and the pomace is formulated to provide specific amounts of soluble and insoluble fiber that work synergistically to control blood glucose levels.
2Reliability
If high fiber dietary supplements are used to control blood glucose, then carbohydrate absorption is reduced, but they may significantly alter food intake and cause digestive discomfort
Solution Approach 1:
The patent uses natural fruit and vegetable pomace that closely copies the structure and composition of whole fruits and vegetables, providing fiber in its natural matrix form rather than as isolated supplements. This allows the pomace to modulate carbohydrate absorption while maintaining compatibility with normal dietary patterns and avoiding the digestive issues associated with concentrated fiber supplements.
Solution Approach 2:
The patent creates a composite material consisting of fruit or vegetable pomace combined with carbohydrate sources. The pomace acts as a matrix that incorporates carbohydrates in a way that slows their absorption without requiring separate fiber supplements, thus modulating carbohydrate uptake while preserving normal food intake patterns.
3Reliability
If pharmaceutical drugs like metformin or acarbose are used to treat type 2 diabetes, then blood glucose levels are controlled, but long-term use requires ongoing medical treatment and may not address underlying metabolic issues
Solution Approach 1:
The patent employs fruit and vegetable pomace as a preliminary dietary intervention that can prevent or delay the onset of type 2 diabetes by modulating carbohydrate absorption before blood glucose levels become severely elevated. This preliminary dietary approach may reduce or delay the need for long-term pharmaceutical intervention, addressing the underlying metabolic issues through nutrition rather than symptom management.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The administration of fruit or vegetable pomace maintains normal blood glucose levels, treats or prevents type 2 diabetes, and aids in weight management without significantly altering food intake, promoting a healthy intestinal microbiome and reducing the risk of related conditions.
Implementation Method 1
a dietary fiber mixture beneficially alters carbohydrate uptake in the gastrointestinal (GI) system
Implementation Method 2
rich in a mixture of soluble and insoluble dietary fibers
Data Source
AI summary
Methods of improving mammalian carbohydrate metabolism and treating, preventing, or halting the progression of type 2 diabetes mellitus involve the consumption of a nutritional composition containing fruit or vegetable pomace. The pomace is produced from native plant tissue and contains a mixture of soluble and insoluble fiber. Periodic consumption of the composition normalizes blood glucose concentration and controls body weight.