Pomegranate Rind Hydrolysate Composition for Multi-Pathway Acne Control
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Solution Overview
Problem
Existing anti-acne treatments, particularly those of natural origin, are ineffective in addressing the multiple biological components of acne, including changes in sebogenesis, hyperkeratinization, inflammation, and alterations in the cutaneous microbiota, as they primarily target only one or two components.
Innovation Solution
A cosmetic or dermatological active ingredient comprising a hydrolysate of the rind of immature Punica granatum fruits, obtained through enzymatic hydrolysis, which targets all four major components of acne: sebogenesis, hyperkeratinization, inflammation, and changes in the microbiota.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If existing natural anti-acne treatments are used, then they provide some therapeutic effect, but they only target one or two biological components of acne instead of all four major components
Solution Approach 1:
The patent applies universality by formulating a cosmetic composition that simultaneously addresses all four major biological components of acne (sebogenesis, hyperkeratinization, inflammation, and microbiota alterations) through a combination of active ingredients, rather than targeting only one or two components as conventional treatments do
2Reliability
If synthetic anti-acne products are used, then they can effectively treat acne, but they are not of natural origin which limits consumer acceptance
Solution Approach 1:
The patent applies composite materials by creating a formulation that combines multiple natural-derived active ingredients (fruit extracts, plant extracts, and their hydrolysates) to achieve comprehensive anti-acne efficacy comparable to synthetic products while maintaining natural origin status for consumer acceptance
3Ease of manufacture
If conventional extraction methods are used for pomegranate rind, then the extraction process is simple, but the extract does not produce satisfactory results in combating all biological components of acne
Solution Approach 1:
The patent applies parameter changes by modifying the extraction parameters - using enzymatic hydrolysis instead of conventional extraction methods, and selecting immature fruits at a specific ripening stage - to enhance the anti-acne efficacy of the pomegranate rind extract while maintaining manufacturing feasibility
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The active ingredient effectively normalizes sebaceous gland activity, reduces hyperkeratinization, controls inflammation, and regulates the cutaneous microbiota, thereby providing comprehensive acne prevention and treatment.
Implementation Method 1
The subject matter of the invention is a cosmetic or dermatological active ingredient comprising at least one particular extract of Punica granatum. Punica granatum, or pomegranate, is well known and widely used. The inventor has selected a precise stage in the ripening of Punica granatum fruits and a particular type of extraction. Indeed, surprisingly, the specific choice of immature fruits of Punica granatum combined with enzymatic hydrolysis makes it possible to effectively improve the anti-acne effect
Data Source
AI summary
The invention relates to a cosmetic or dermatological active ingredient comprising at least one hydrolysate of the rind of immature fruits of Punica granatum, which may be in liquid form, in solid form, or in the form of a film. The invention further relates to a composition comprising this active ingredient, to a method for obtaining the same, as well as to the use thereof for preventing and/or combating acne.