Portable Auto-Injector with Segmented Dry-Liquid Storage

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Solution Overview

Problem

Auto-injectors face challenges in size, portability, and shelf-life due to their bulkiness and the need for immediate reconstitution of medications, leading to potential ineffectiveness in emergency situations.

Innovation Solution

A portable auto-injector design with separate chambers for dry and liquid medicaments, utilizing a sliding mechanism and pre-stored energy source for mixing and delivery, ensuring proper storage and reconstitution before injection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If medication is stored in liquid state for immediate use, then speed of administration is improved, but shelf-life and temperature susceptibility deteriorate

Engineering Contradiction:
Improvespeed of administrationVSAvoidshelf-life
Core Design Contradiction:
SpeedVSReliability

Solution Approach 1:

The device divides the medication storage into separate compartments: a first chamber for liquid medication and a second chamber for dry powder medication. This segmentation allows each component to be stored in its optimal state (liquid for quick administration, dry for long shelf-life) while maintaining the capability for rapid mixing and administration when needed.

Inventive Principle:
Principle #1Segmentation

2Reliability

If auto-injector size is increased to ensure proper mixing and delivery mechanisms, then reliability of medication delivery is improved, but portability and ease of carrying deteriorate

Engineering Contradiction:
Improvereliability of medication deliveryVSAvoidportability
Core Design Contradiction:
ReliabilityVSWeight of moving object

Solution Approach 1:

The second chamber containing dry powder medication is positioned within or adjacent to the first chamber in a nested arrangement. The mixing assembly and delivery mechanism are integrated into the chamber structure, allowing compact packaging that reduces overall device size and weight while maintaining reliable mixing and delivery functionality.

Inventive Principle:
Principle #7Nested doll (Nesting)

3Reliability

If separate chambers for dry and liquid components are implemented, then shelf-life is improved, but device complexity increases

Engineering Contradiction:
Improveshelf-lifeVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The device merges multiple functions into integrated components: the chamber walls serve as both storage barriers and mixing surfaces, the plunger mechanism simultaneously pushes liquid and activates dry powder mixing, and the delivery system handles both liquid and reconstituted medication. This functional integration reduces the number of separate parts needed despite the multi-chamber design.

Inventive Principle:
Principle #5Merging (Combining)

4Reliability

If mixing mechanism is added to ensure complete reconstitution, then efficacy of medication is improved, but device complexity and size increase

Engineering Contradiction:
Improveefficacy of medicationVSAvoidmixing mechanism complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The mixing mechanism is designed to be self-activating through the existing plunger operation. When the plunger pushes the liquid medication from the first chamber, it automatically enters the second chamber and mixes with the dry powder through the chamber geometry and flow dynamics, eliminating the need for separate mixing actuators or complex mechanical mixing devices.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The design enhances the shelf-life and portability of auto-injectors by maintaining medication potency and reducing temperature susceptibility, ensuring the user has an effective device when needed.

Implementation Method 1

the first medicament component of the first chamber to mix with a second medicament stored outside the first chamber

Methodology Applied
Scientific EffectMixing:

Implementation Method 2

an actuation assembly that upon actuation causes the valve to open, and causes one of the chambers to slidably move relative to the other

Methodology Applied
Scientific EffectMechanical force: Mechanical Force

Data Source

PatentUS10350364B2Portable Drug Mixing and Delivery Device and Associated Methods
Publication Date: 2019.07.16 WINDGAPLEGACYCO LLC
  • US10350364B2 patent drawing
  • US10350364B2 patent drawing
  • US10350364B2 patent drawing

AI summary

A portable auto-injector configured to store a dry medication separately from a liquid component, wherein removal of a cap operates a first actuation mechanism which opens a valve between a first and second chamber that are slidably movable relative to each other and thus allows for the initiation of a mixing step prior to injection. An extendable needle guard is provided over the delivery assembly which prevents premature injection as well as inadvertent sticks or other cross contamination of a needle. The needle guard can also form part of a secondary trigger mechanism which injects the mixed components after the mixing stage is complete.