Portable Biomarker Test Apparatus for On-Site Animal Health Screening
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Solution Overview
Problem
Current methods for diagnosing and treating health issues in animals and humans are inefficient, particularly in identifying specific disease variations and providing targeted treatments, leading to delayed medication development and ineffective resource allocation.
Innovation Solution
A portable test apparatus that uses biomarker antibodies and antigens for on-site analysis, allowing for rapid identification of health conditions through lateral flow tests and subsequent data transmission for remote validation, enabling personalized treatment plans and immediate action.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If traditional centralized diagnostic methods are used, then comprehensive analysis can be performed, but testing time and resource allocation are excessive
Solution Approach 1:
The diagnostic system is segmented into two parts: a portable point-of-care device for rapid initial testing and a centralized laboratory system for comprehensive analysis. The portable device performs quick screening using simplified assays, while the laboratory system handles complex confirmatory testing, thereby reducing overall testing time while maintaining diagnostic accuracy.
Solution Approach 2:
The portable point-of-care device performs preliminary diagnostic testing at the site of care, enabling early detection and immediate preliminary results. This preliminary action allows for rapid identification of positive cases that require further investigation, reducing the time lost in transporting samples and enabling faster intervention.
2Reliability
If comprehensive testing is performed on all animals in a herd, then widescale health problems can be identified, but the complexity and cost of testing increases
Solution Approach 1:
The testing system is segmented into portable point-of-care devices for rapid screening and centralized laboratory systems for comprehensive analysis. This segmentation enables large-scale screening of entire herds using simple, fast tests, while only suspicious cases require complex confirmatory testing, thereby maintaining high monitoring coverage without proportionally increasing system complexity.
Solution Approach 2:
Complex laboratory-based diagnostic mechanisms are replaced with simplified immunochromatographic assays in the portable device. These simplified mechanisms use antibody-antigen binding reactions that can be performed without complex instrumentation, enabling comprehensive herd screening with reduced system complexity.
3Measurement precision
If multiple variations of health problems are tested for, then accurate diagnosis can be provided, but the number of required tests and funding requirements increase
Solution Approach 1:
Multiple disease detection capabilities are merged into a single integrated portable device. The device can simultaneously or sequentially test for multiple different diseases using different antibody strips, reducing the total number of separate tests required while maintaining the ability to accurately identify specific disease variations.
Solution Approach 2:
The portable diagnostic device is designed with universal functionality to detect multiple different diseases and health conditions. By using a single multi-functional device with interchangeable or multiplexed assay strips, the system reduces the quantity of separate testing equipment and reagents needed compared to using dedicated tests for each disease.
4Productivity
If rapid on-site testing is performed, then immediate results can be obtained, but the precision and comprehensiveness of analysis may be reduced
Solution Approach 1:
The diagnostic process is segmented into rapid screening using the portable point-of-care device and comprehensive confirmation using centralized laboratory systems. The portable device provides quick initial results with sufficient precision for screening, while the laboratory system provides definitive diagnostic precision for complex cases, combining both speed and accuracy.
Solution Approach 2:
The portable point-of-care device acts as an intermediary between field conditions and centralized laboratory analysis. It performs rapid preliminary testing that bridges the gap between immediate on-site needs and comprehensive laboratory capabilities, providing results that are sufficiently precise for initial decision-making while enabling faster overall diagnosis through parallel processing.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Facilitates immediate and effective health management by providing accurate, on-site diagnosis and personalized treatment recommendations, reducing the burden on specialists and streamlining drug development while minimizing unnecessary medication use.
Implementation Method 1
the analysis means allows the analysis of biomarker antibodies and/or antigens
Data Source
AI summary
An apparatus and a method for undertaking a test on a person or animal on site. The apparatus includes a body having a portion for contact with a sample obtained from a person/or animal and analysis means, typically one or more biomarkers, to allow the test to be analyzed. Indication means can be provided on the apparatus to illustrate the test result on site and/or the test results can be captured and transmitted to a remote location for subsequent analysis. If deemed required after the analysis, one or more actions to be taken can be recommended to a person who has been tested and/or the person performing the test while at the location of the test and thereby allow rapid testing and actions to be performed if required.