Portable Cryosurgical Device With Zero-Dead-Volume Cryogen Delivery

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Solution Overview

Problem

Existing cryosurgical devices are complex, costly, and inefficient in delivering high-pressure, low-boiling point cryogens, often requiring specialized equipment, posing safety hazards and limiting treatment duration due to limited reservoirs and awkward patient positioning.

Innovation Solution

A portable, ergonomic cryosurgical device with a solenoid valve system and omni-directional wand that delivers metered doses of cryogenic fluids like carbon dioxide and nitrous oxide, featuring a quick-change cylinder system and real-time cryogen level indication, ensuring consistent treatment times and ease of use.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Temperature

If conventional cryosurgical devices use liquid nitrogen or complicated valving mechanisms to deliver liquefied gases, then colder temperatures can be achieved, but the device structure becomes complex and manufacturing cost increases

Engineering Contradiction:
Improvecryogenic temperatureVSAvoidvalving mechanism complexity
Core Design Contradiction:
TemperatureVSDevice complexity

Solution Approach 1:

The patent extracts the complex valving mechanism from the system by using a simple push-button actuator that directly opens a valve in the cryogen container, eliminating the need for complicated external valving mechanisms while maintaining the ability to deliver cold cryogenic temperatures

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system uses the pressure of the stored cryogenic gas itself to drive the dispensing process, with the gas pressure automatically controlling the flow through the needle valve without requiring external mechanical valving mechanisms

Inventive Principle:
Principle #25Self-service

2Ease of operation

If handheld pressurized containers use compressed gases like butane or propane for cryosurgery, then portability is improved, but the evaporation rate becomes too slow and treatment duration is limited

Engineering Contradiction:
ImproveportabilityVSAvoidtreatment duration
Core Design Contradiction:
Ease of operationVSDuration of action of moving object

Solution Approach 1:

The patent changes the physical parameters of the system by switching from low-pressure compressed gases to high-pressure liquid cryogens stored at their boiling points, which dramatically increases the evaporation rate and extends treatment duration while maintaining portability

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system utilizes the phase transition of cryogenic liquids (liquid to gas) at controlled rates by adjusting the valve opening, allowing sustained treatment duration through regulated evaporation of the liquid cryogen

Inventive Principle:
Principle #36Phase transitions

3Temperature

If cryosurgical devices use high-pressure liquefied gases with low boiling points, then colder temperatures are achieved, but safety hazards increase due to handling difficulties

Engineering Contradiction:
Improvecryogenic temperatureVSAvoidsafety hazards
Core Design Contradiction:
TemperatureVSObject-affected harmful factors

Solution Approach 1:

The patent introduces an intermediary needle valve mechanism that allows precise control of the cryogen flow, mediating between the high-pressure storage container and the application point to safety manage the release of cold cryogenic temperatures

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system uses a small opening in the needle valve to control the cryogen flow rate, applying only the necessary amount of cold cryogen needed for treatment rather than allowing uncontrolled release, thereby reducing safety hazards

Inventive Principle:
Principle #16Partial or excessive action

4Volume of moving object

If limited reservoirs are used in portable cryosurgical devices, then device size is reduced, but the effective temperature is reached for only a short period

Engineering Contradiction:
Improvereservoir volumeVSAvoideffective temperature duration
Core Design Contradiction:
Volume of moving objectVSDuration of action of moving object

Solution Approach 1:

The patent ensures continuous useful action by maintaining the cryogen reservoir at its boiling point through pressure equilibrium, allowing the liquid to continuously evaporate and maintain effective cryogenic temperatures throughout the treatment duration without interruption

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device provides economical, reliable, and versatile cryosurgical treatments with customizable freeze-thaw cycles, minimizing damage to healthy tissue and reducing per-use costs by allowing multiple uses without disposable components.

Implementation Method 1

The solenoid valve includes a valve body with a valve seat, an inlet port on an inlet side of the valve seat that introduces the cryogen from the cryogen source into the valve body, an outlet port on an outlet side of the valve seat that receives the cryogen from the valve body, and a piston movable to cause the valve seat to move from a closed position preventing passage of the cryogen from the inlet side of the valve seat to the outlet side of the valve seat to an open position permitting the passage of the cryogen from the inlet side of the valve seat to the outlet side of the valve seat

Methodology Applied
Scientific EffectSolenoid actuation: Solenoid

Implementation Method 2

Such cryosurgical devices generally rely upon a liquefied (compressed) gas, such as butane, propane, or dimethyl ether (DME), and others to rapidly cool an applicator tip or 'bud' based on the principles of 'heat of vaporization.' As the compressed gas flows to and contacts a surface of an applicator, such as a porous applicator bud, rapid evaporation of the gas causes the applicator surface to cool to temperatures that are lower than the boiling point of the liquefied gas alone

Methodology Applied
Scientific EffectHeat of vaporization: Evaporation

Implementation Method 3

Direct spray methods for such localized freezing are governed by the 'Joules Thomson' effect due to expansion of the cooling liquid

Methodology Applied
Scientific EffectJoule-Thomson effect: Joule-Thomson Effect

Data Source

PatentEP3709917B1Portable electro-mechanical cryosurgical device
Publication Date: 2025.07.23 CRYOCONCEPTS
  • EP3709917B1 patent drawingFigure 1A~1B
  • EP3709917B1 patent drawingFigure 2
  • EP3709917B1 patent drawingFigure 3

AI summary

The portable cryosurgical device is economical, easy to use and operate, and delivers cryogenic material such as nitrous oxide and carbon dioxide gas in any direction or orientation. The delivered materials destroy target tissue using extremely cold temperatures and the abrasives formed when the cryogenic material becomes a solid. The device includes a portable countertop enclosure housing a cryogen source, a cryogen flow tube in fluid communication with the cryogen source, and a flow path assembly. The flow path assembly includes a valve between the cryogen source and the cryogen flow tube having substantially zero dead volume. The flow path assembly can include a quick-connect cryogen tank adapter and an in-line cryogen filter. The flow path assembly delivers liquefied compressed gas from the cryogen source to a terminal end of the cryogen flow tube without a phase change occurring in the flow path.