Portable Oxygen Source for Tissue Perfusion
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Solution Overview
Problem
Conventional perfusion systems for preserving tissues outside the body require electrical components and complex setups, which can be cumbersome and unsafe for transport, especially in commercial aviation.
Innovation Solution
A portable oxygen source, such as an oxygen concentrator or generator, is used to both oxygenate and pump fluid through the tissue vasculature, eliminating the need for electrical components and providing a safer, more simplified perfusion system.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional perfusion systems use electrical components and complex setups, then reliable tissue preservation is achieved, but the system becomes cumbersome and unsafe for transport
Solution Approach 1:
The patent removes electrical components from the perfusion system, extracting the harmful element (electrical complexity) while retaining the core function of tissue preservation through mechanical pumping and oxygenation
Solution Approach 2:
The portable oxygen source serves multiple functions: it provides oxygenation to the tissue and simultaneously acts as the pressure source to pump perfusate through the vasculature, eliminating the need for separate electrical pumps
2Ease of operation
If conventional perfusion systems use electrical pumps, then fluid pumping is achieved, but safety during transport is compromised
Solution Approach 1:
The patent replaces electrical pumps with a mechanically-driven system where a portable oxygen source provides both the oxygen supply and the mechanical pressure to drive fluid flow through the tissue
Solution Approach 2:
The portable oxygen source serves itself by using its own pressurized gas output to drive the perfusion process, eliminating the need for external electrical power sources or separate pumping mechanisms
3Device complexity
If portable oxygen source is used for both oxygenation and pumping, then device complexity is reduced, but pressure gradient requirements increase
Solution Approach 1:
The patent changes the pressure parameter of the oxygen source by using it in a pressurized state, allowing the same device to fulfill both oxygenation and pumping functions by leveraging the pressure gradient it naturally generates
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution allows for efficient tissue preservation by delivering oxygen and nutrients while removing waste products, with the system being safer and more transport-friendly due to its reduced complexity and absence of electrical components.
Implementation Method 1
The portable oxygen source can provide oxygen and apply a pressure gradient to a flow of the oxygen
Implementation Method 2
pumping fluid and oxygenate that fluid for tissue preservation by perfusion
Data Source
AI summary
The present disclosure includes a system to preserve tissue and associated methods. The system can include a portable oxygen source to provide oxygen and apply a pressure gradient to a flow of the oxygen, an organ preservation system having an inlet to fluidly couple to vasculature of the tissue, and an oxygen line to fluidly couple the portable oxygen source to the organ preservation system at the inlet, wherein the portable oxygen source is to apply the pressure gradient to pump fluid containing the oxygen through the organ preservation system.