Portable Perfusion Pump for Organ Procurement

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Solution Overview

Problem

Traditional organ procurement methods lack precise controlled delivery of preservation solutions and suitable systems for maintaining optimal perfusate parameters during organ procurement, often performed by mobile staff without reliable systems for consistent and controlled solution delivery.

Innovation Solution

An organ procurement perfusion pump system comprising a portable enclosure with a pump, sensors, and thermal control, connected to a control module that regulates perfusate parameters via wireless communication with a mobile device, ensuring controlled flow, pressure, and temperature management.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional organ procurement methods are used, then mobile staff can perform procurement procedures, but there is no precise controlled delivery of preservation solution and no suitable systems for maintaining optimal perfusate parameters

Engineering Contradiction:
Improvecontrolled delivery of preservation solutionVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple functions (pump, thermal control, sensors, and control module) into a single integrated portable enclosure. This merging resolves the contradiction by providing precise controlled delivery of preservation solution while maintaining portability and reducing the complexity of coordinating multiple separate devices.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The portable enclosure serves multiple functions simultaneously: it houses the pump, provides thermal control through heating/cooling elements, contains sensors for monitoring, and includes a control module for automation. This multi-functionality enables precise perfusate delivery without requiring separate specialized equipment for each function.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If conventional methods are used, then organ procurement can be performed by mobile staff, but there are no suitable systems for maintaining optimal perfusate parameters during the procedure

Engineering Contradiction:
Improvemaintenance of optimal perfusate parametersVSAvoidoperation simplicity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent incorporates sensors that continuously monitor perfusate parameters (temperature, flow, pressure) and feed this information back to the control module. The control module automatically adjusts the pump and thermal control elements to maintain optimal parameters, eliminating the need for manual monitoring and adjustment while ensuring reliable parameter maintenance.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system performs self-regulation through automated feedback control. The control module continuously adjusts pump speed and thermal elements based on sensor input, allowing the system to maintain optimal perfusate parameters autonomously without requiring constant manual intervention, thus improving both reliability and ease of operation.

Inventive Principle:
Principle #25Self-service

3Reliability

If precise controlled delivery of preservation solution is implemented, then unexplained failures in organ recipients can be reduced, but the system becomes more complex

Engineering Contradiction:
Improveorgan recipient outcomesVSAvoidsystem structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

By integrating the pump, thermal control system, sensors, and control module into a single portable enclosure, the patent achieves precise controlled delivery of preservation solution that improves organ recipient outcomes while avoiding the complexity of coordinating multiple separate devices. The unified design maintains reliability without proportionally increasing system complexity.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides consistent, reliable, and measurable delivery of preservation solutions, reducing unexplained failures in organ recipients by automating perfusate parameter control and improving outcomes through precise management of perfusate flow, pressure, and temperature.

Implementation Method 1

a pump disposed within the enclosure configured to cause flow the line

Methodology Applied
Scientific EffectPump: Pump

Implementation Method 2

the thermal control cavity can be configured to contain and/or insulate passive temperature regulation media

Methodology Applied
Scientific EffectThermal insulation: Thermal Insulation

Implementation Method 3

an active cooling system in thermal communication with the thermal control cavity configured to regulate the temperature of the perfusate

Methodology Applied
Scientific EffectCooling: Cooling

Implementation Method 4

a flow meter configured to read a flow in the fluid line

Methodology Applied
Scientific EffectFlow measurement:

Implementation Method 5

a pressure sensor configured to read a pressure in the fluid line

Methodology Applied
Scientific EffectPressure measurement:

Implementation Method 6

a temperature sensor configured to read temperature of the perfusate in the fluid line

Methodology Applied
Scientific EffectTemperature measurement:

Data Source

PatentUS20240008475A1Organ procurement devices, systems, and methods
Publication Date: 2024.01.11 SHEA NICHOLAS J
  • US20240008475A1 patent drawing
  • US20240008475A1 patent drawing
  • US20240008475A1 patent drawing

AI summary

An organ procurement perfusion pump system can include a portable enclosure, a fluid line, a pump disposed within the enclosure configured to cause flow the line, one or more sensors disposed in functional communication with the fluid line, and a thermal control cavity within the enclosure configured to contain one or more perfusate containers which connect to the fluid line to regulate the temperature of the perfusate. The system can further include a control module operatively connected to the pump and the one or more sensors, and configured to control the pump.