Portable Reader Module Light-Shielded Housing for Assay Analysis

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Solution Overview

Problem

Existing portable reader modules for immunoassays and chromatographic assays lack reliable quantitative analysis capabilities, as they are prone to interference from ambient light and do not provide a controlled environment for accurate image analysis.

Innovation Solution

A portable reader module with a housing that includes a light-shielded internal space, a first receptacle for a portable device with an imager, and a second receptacle for a cartridge, featuring a light-deflecting optical element and an illuminating path to ensure controlled lighting conditions, allowing for precise image capture and processing of test results.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a portable reader module is used for assay analysis, then portability and ease of operation are improved, but measurement precision and reliability deteriorate due to ambient light interference

Engineering Contradiction:
ImproveportabilityVSAvoidquantitative analysis accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent implements a light-shielded internal space that creates a controlled environment isolated from ambient light interference. This allows the portable reader to maintain measurement precision comparable to stationary devices while preserving portability, as the light shielding is integrated into the compact housing structure.

Inventive Principle:
Principle #39Inert atmosphere (Inert environment)

Solution Approach 2:

The patent introduces an adapter as an intermediary component that holds the cartridge and positions it precisely within the light-shielded internal space. This adapter mediates between the portable device and the assay cartridge, ensuring proper alignment and optical path establishment while maintaining the controlled environment.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If a light-shielded internal space is implemented, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvequantitative analysis accuracyVSAvoidhousing structure complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent merges the light-shielding function with the housing structure itself, integrating the controlled environment creation into the basic device architecture rather than adding separate shielding components. The housing simultaneously provides structural support and light isolation, reducing overall complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The housing structure serves multiple functions: it provides mechanical support, defines the internal space, shields against ambient light, and houses the optical components. This multi-functionality reduces the number of separate components needed, keeping the device relatively simple despite the controlled environment requirement.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If an adapter with magnetic bodies and metal pins is used to hold the cartridge, then reliability of cartridge positioning is improved, but device complexity increases

Engineering Contradiction:
Improvecartridge holder positioningVSAvoidadapter structure complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent replaces purely mechanical fastening mechanisms with a magnetic coupling system. The magnetic bodies in the adapter interact with metal pins on the cartridge holder to provide secure, reliable positioning without requiring complex mechanical interlocks or multiple fastening components, simplifying the overall adapter structure.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables reliable quantitative analysis of assays by minimizing ambient light interference and providing a controlled environment for image acquisition, leading to accurate and consistent test result processing.

Implementation Method 1

A light-deflecting optical element is arranged within the internal space of the housing to define an optical path between the first optical entrance and the second optical entrance

Methodology Applied
Scientific EffectLight reflection: Reflection

Implementation Method 2

One of the cartridge holder and the cartridge interface comprises magnetic bodies and the other one of the cartridge holder and the cartridge interface comprises metal pins or discs which cooperate together with the magnetic bodies to hold the cartridge holder in place relative to the cartridge interface

Methodology Applied
Scientific EffectMagnetic attraction: Magnetism

Data Source

PatentEP2921846B1Portable reader module, portable reader, and method for quantitative analysis of an assay
Publication Date: 2023.10.25 MICRODISCOVERY
  • EP2921846B1 patent drawingFigure 1A~1B
  • EP2921846B1 patent drawingFigure 2A~2B
  • EP2921846B1 patent drawingFigure 3~4B

AI summary

A portable reader module includes a housing (100, 101) having an internal space (102), and a first receptacle (110) configured to removably receive a portable device (300) having an imager, wherein the first receptacle (110) includes a first optical entrance (420) for the imager to the internal space (102) of the housing (100, 101). The housing (100, 101) further includes a second receptacle (120) configured to removably receive a cartridge (500), wherein the second receptacle (120) includes a second optical entrance (122) to the internal space (102) of the housing (100, 101) so that the cartridge (500) is visible to and from the internal space (102). A light-deflecting optical element (450) is arranged within the internal space (102) of the housing (100, 101) to define an optical path between the first optical entrance (420) and the second optical entrance (122). An illuminating path for illuminating the cartridge (500) is defined in the housing (100, 101). The housing (100, 101)is configured to allow the internal space (102) to be light-shielded.