Portable Ventilator Valve Control for Low-Resource Settings

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Solution Overview

Problem

Current ventilators are expensive, complex, and unsuitable for low-resource environments, particularly during pandemics, as they require constant power and are not designed to handle acute respiratory distress syndrome (ARDS) patients effectively, with a significant disparity in availability between wealthy and impoverished nations.

Innovation Solution

A portable ventilator system that uses a source of pressurized gas, a patient vessel, and a valve assembly controlled by a controller to deliver ventilation gas, allowing for inexpensive mass production and operation without external power or compressed oxygen, with features like PEEP and spontaneous assist modes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current ventilator designs are used, then clinical functionality is achieved, but cost and device complexity increase significantly

Engineering Contradiction:
Improveclinical functionalityVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The ventilator is divided into distinct functional modules: a gas source module (compressor or oxygen tank), a control module (microcontroller), a delivery module (valves and tubing), and a monitoring module (sensors). This segmentation allows each component to be optimized independently and simplifies manufacturing and assembly while maintaining full clinical functionality.

Inventive Principle:
Principle #1Segmentation

2Reliability

If current ventilator designs are used, then ventilation capability is provided, but power consumption increases and portability decreases

Engineering Contradiction:
Improveventilation capabilityVSAvoidpower consumption
Core Design Contradiction:
ReliabilityVSUse of energy by moving object

Solution Approach 1:

The ventilator operates in periodic cycles of inspiration and expiration, with the compressor or oxygen tank activating only during the inspiration phase. The control system timing the valve operations to open and close in rhythmic sequences, allowing the motor to remain stationary during expiration, thereby reducing overall power consumption while maintaining effective ventilation capability.

Inventive Principle:
Principle #19Periodic action

3Reliability

If sophisticated ICU machine features are included, then treatment capability for ARDS is improved, but manufacturing cost increases

Engineering Contradiction:
Improvetreatment capabilityVSAvoidmanufacturing cost
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The ventilator employs disposable components such as single-use filters, disposable tubing sets, and replaceable battery packs. This approach allows the main device to remain simple and inexpensive to manufacture, while critical components that require high precision or sterilization can be replaced rather than rebuilt, reducing overall manufacturing costs while maintaining ARDS treatment capability.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

4Reliability

If external oxygen supply is required, then oxygen delivery is ensured, but system complexity and resource dependency increase

Engineering Contradiction:
Improveoxygen deliveryVSAvoidresource dependency
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The ventilator incorporates an integrated oxygen generation system using a small-scale molecular sieve compressor or chemical oxygen generator that produces oxygen on-demand from ambient air or stored chemicals. This self-service capability eliminates dependency on external oxygen tanks or hospital oxygen supplies, reducing system complexity and resource dependency while ensuring reliable oxygen delivery for ARDS patients.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides clinical functionality similar to sophisticated ICU machines at a significantly lower cost, operating efficiently with minimal power requirements and no need for external oxygen, making it suitable for low-resource settings and emergency situations.

Implementation Method 1

a compressor, which compresses the gas at a variable operating rate

Methodology Applied
Scientific EffectCompression: Compression

Implementation Method 2

A valve assembly communicating with the gas source via a source line, the patient vessel

Methodology Applied
Scientific EffectPressure gradient: Pressure Gradient

Implementation Method 3

a first pressure sensor coupled to the patient vessel for detecting the pressure of ventilation gas within the patient vessel

Methodology Applied
Scientific EffectPressure sensing:

Data Source

PatentEP2498849B1Portable ventilator
Publication Date: 2022.08.10 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
  • EP2498849B1 patent drawingFigure 1
  • EP2498849B1 patent drawingFigure 2
  • EP2498849B1 patent drawingFigure 3A~3B

AI summary

A ventilator includes a compressor, a storage vessel, a valve assembly communicating with the compressor, the storage vessel, and an inhalation line. A controller directs the valve assembly between a storage configuration where ventilation gas is delivered from the compressor into the storage vessel, and a delivery configuration where ventilation gas is delivered from the storage vessel to the inhalation line. The controller is coupled to a pressure sensor for detecting a first pressure within the storage vessel when the valve assembly is directed to the delivery configuration, and detecting subsequent pressure while ventilation gas is delivered from the storage vessel to the inhalation line, the controller determining the volume of ventilation gas delivered to the patient based at least in part on the difference between the first pressure and the subsequent pressure.