Potassium Titanium Oxalate Tooth Sensitivity Treatment

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Solution Overview

Problem

Current tooth sensitivity treatments, such as those containing strontium disodium ethylene diamine tetraacetate, potassium nitrate, and potassium oxalate, are not completely effective in mitigating dentinal sensitivity due to inadequate occlusion of dentinal tubules, highlighting a need for compositions with improved affinity for dentin and enhanced tubule occlusion.

Innovation Solution

The development of an oral composition comprising specific compounds like potassium titanium oxide oxalate, which forms a protective barrier on teeth, occludes exposed dentinal tubules, and includes additional desensitizing agents, solvents, and pH buffers, applied in multiple applications to achieve significant tubule occlusion.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional occluding agents (potassium nitrate, potassium oxalate, strontium disodium ethylene diamine tetraacetate) are used, then tooth sensitivity treatment is provided, but the occlusion of dentinal tubules is inadequate and effectiveness is limited

Engineering Contradiction:
Improveeffectiveness of dentinal tubule occlusionVSAvoidinsufficient occlusion leading to persistent sensitivity
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent changes the chemical composition parameters by introducing titanium oxide as a novel occluding agent combined with potassium oxalate, creating a new chemical system that forms more effective precipitates in dentinal tubules compared to traditional single-agent formulations

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention uses a composite occluding system combining titanium oxide particles with potassium oxalate, where the combination creates synergistic effects that enhance tubule occlusion effectiveness beyond what either agent could achieve alone

Inventive Principle:
Principle #40Composite materials

2Reliability

If multiple applications are required for effective occlusion, then treatment effectiveness improves, but treatment time and complexity increase

Engineering Contradiction:
Improveocclusion effectivenessVSAvoidtreatment duration
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent modifies the concentration parameters of the occluding agents, using optimized concentrations of titanium oxide and potassium oxalate that enhance precipitate formation efficiency, allowing for reduced treatment duration while maintaining occlusion effectiveness

Inventive Principle:
Principle #35Parameter changes

3Reliability

If precipitate formation is enhanced for better occlusion, then tubule occlusion improves, but stability against sonication may be compromised

Engineering Contradiction:
Improvetubule occlusion percentageVSAvoidprecipitate stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The invention creates a composite precipitate structure where titanium oxide particles are embedded within potassium oxalate precipitates, forming a hierarchical composite that provides both high occlusion percentage and enhanced stability against sonication through the synergistic interaction of the two materials

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively reduces tooth sensitivity by forming a stable precipitate that occludes a high percentage of dentinal tubules, providing long-lasting desensitization and improved stability against sonication, surpassing the efficacy of traditional occluding agents.

Implementation Method 1

contacting the teeth with the composition in the presence of calcium for at least 20 seconds wherein the compound forms a precipitate with the calcium on or in the vicinity of the teeth

Methodology Applied
Scientific EffectPrecipitation: Precipitation

Implementation Method 2

forming a stable precipitate that occludes a high percentage of dentinal tubules, providing long-lasting desensitization

Methodology Applied
Scientific EffectDeposition: Deposition (physical)

Data Source

PatentEP2281546B1Tooth sensitivity treatment compositions
Publication Date: 2018.09.19 JOHNSON & JOHNSON CONSUMER INC
  • EP2281546B1 patent drawingFigure 1~4
  • EP2281546B1 patent drawingFigure 5~8
  • EP2281546B1 patent drawingFigure 9~10

AI summary

A tooth sensitivity treatment composition is disclosed. The composition includes a compound of Formula I          M1-A-M2-B-M3     (I) wherein: M1 and M3 are, independently, a monovalent or divalent metal; M2 is a polyvalent metal or metal oxide; and A and B are, independently, selected from the group consisting of C2 - C6 diacids, triacids, and tetraacids. Methods for treating tooth sensitivity are also disclosed.