PPGI Dental Pulp Vitality Imaging via Transillumination

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Solution Overview

Problem

Current dental pulp vitality testing methods, such as thermal and electric pulp sensibility tests, are indirect and prone to false results, while radiographs provide limited diagnostic utility for soft pulp tissue and are costly. Existing techniques like Laser Doppler flowmetry and pulse oximetry are susceptible to noise contamination and external errors, making them unreliable for assessing pulp health.

Innovation Solution

A photoplethysmography imaging (PPGI) system using a spatial array of sensors to capture 2-dimensional images of tissue perfusion, differentiating blood-perfused regions from non-perfused areas by analyzing pulsatile signals, providing a direct and reliable assessment of pulp vitality through transillumination and image processing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional thermal and electric pulp sensibility tests are used, then high sensitivity in detecting pulp health is achieved, but false positive or negative results occur and no information about pulp tissue state is provided

Engineering Contradiction:
Improvepulp health detection accuracyVSAvoidtest result reliability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent replaces traditional mechanical/electrical sensing methods (thermal and electric pulp sensibility tests) with an optical measurement system. The PPGI system uses light sources and photodetectors to measure blood perfusion in the pulp, substituting the mechanical/electrical stimulation approach with non-contact optical detection that directly visualizes tissue perfusion status.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent utilizes photoplethysmography which detects color changes in the tooth caused by pulsatile blood flow in the pulp. The system measures optical absorption changes at different wavelengths (visible-red and near-infrared) that correspond to blood oxygenation levels and perfusion changes, enabling direct visualization of pulp vitality through color/optical property variations.

Inventive Principle:
Principle #32Color changes

2Loss of information

If radiographs are administered to assess pulp tissue, then images of enamel and dentin defects are obtained, but limited diagnostic utility for soft pulp tissue is provided and high cost is incurred

Engineering Contradiction:
Improvepulp tissue diagnostic informationVSAvoiddiagnostic cost
Core Design Contradiction:
Loss of informationVSEase of manufacture

Solution Approach 1:

The patent extracts and isolates the specific signal from pulp blood perfusion by using wavelength-specific optical filters and pulse oximetry algorithms. The system separates the pulsatile blood flow signal from static tissue background, extracting only the relevant information about pulp vitality while filtering out unrelated signals from surrounding structures.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent uses light as an intermediary substance to probe the pulp tissue. Instead of using ionizing radiation (X-rays), the system employs visible and near-infrared light that can penetrate tooth structures and interact with blood chromophores in the pulp, providing soft tissue contrast without the costs and limitations of radiographic equipment.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Measurement precision

If Laser Doppler flowmetry is used to assess blood flow, then direct measurement of pulp perfusion is achieved, but susceptibility to noise contamination and external errors increases

Engineering Contradiction:
Improveblood flow measurement accuracyVSAvoidmeasurement reliability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent transitions from point-based Laser Doppler flowmetry measurements to area-based imaging measurements. The PPGI system captures spatially-resolved optical signals across the entire tooth surface, providing a two-dimensional map of pulp perfusion rather than a single point measurement, thereby reducing the impact of localized noise or artifacts.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The patent implements signal processing feedback mechanisms including pulse oximetry algorithms that use ratio calculations at multiple wavelengths to compensate for variations in tissue optics and external interference. The system continuously monitors and adjusts for noise contamination by comparing signals at different wavelengths and using temporal filtering to isolate pulsatile components.

Inventive Principle:
Principle #23Feedback

4Ease of manufacture

If standard pulse oximeters are used to measure blood oxygenation, then cost reduction is achieved, but susceptibility to noise contamination from periodontal tissues increases

Engineering Contradiction:
Improvedevice costVSAvoidmeasurement reliability
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The patent divides the measurement into multiple independent wavelength channels and spatial regions. The PPGI system uses an array of photodetectors that capture light at multiple wavelengths simultaneously, allowing separation of signals from different tissue compartments (pulp vs. periodontal tissues) through spectral unmixing and spatial filtering techniques.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent extends standard pulse oximetry from single-point measurement to imaging across the tooth surface. This spatial dimension allows differentiation between signals originating from the pulp chamber versus surrounding periodontal tissues, enabling rejection of contaminating signals through spatial filtering and region-of-interest analysis.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The PPGI system offers a direct, cost-effective, non-invasive, and radiation-free method for assessing pulp vitality, improving accuracy and reliability over existing techniques, capable of identifying blood flow and regional disruptions indicative of pathology, thus reducing preventable endodontic emergencies.

Implementation Method 1

LDF, a microvascular blood perfusion assessment technique, measures slight shifts in the wavelengths of incident, and reflected light scattered by moving red blood cells

Methodology Applied
Scientific EffectLaser Doppler flowmetry: Doppler Effect

Implementation Method 2

Pulse oximetry measures differences between the intensity of light absorbed by perfused tissue, at multiple wavelengths, to derive blood oxygenation

Methodology Applied
Scientific EffectPulse oximetry: Absorption Spectroscopy

Implementation Method 3

A photodetector identifies absorbance peaks caused by pulsatile blood circulation, and thereby calculates the pulse rate and oxygen saturation level

Methodology Applied
Scientific EffectPhotoplethysmography: Photoelectric Effect

Data Source

PatentUS20210022593A1Photoplethysmography Imaging (PPGI)-Based Pulp Vitality Test
Publication Date: 2021.01.28 NAVY UNITED STATES OF AMERICA AS REP BY SEC OF THE
  • US20210022593A1 patent drawing
  • US20210022593A1 patent drawing
  • US20210022593A1 patent drawing

AI summary

This invention discloses a vitality-based photoplethysmography imaging (PPGI) system capable of determining the pulse frequency within the dental pulp, allowing for direct, accurate, real-time visualization of tooth vitality. The system comprises a transilluminating bitewing, capable of aligning and stabilizing a light source and an intraoral camera, which is operationally connected to a computing device that is equipped with video stabilization and digital signal processing algorithm (Pulp Assessment by Local Observation, i.e. PABLO) to assess pulp vitality via analyzing videos captured with the intraoral camera.