Ingestible Prebiotic–Probiotic–Postbiotic Composition for Gut Health
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Solution Overview
Problem
Existing nutritional compositions fail to effectively improve health outcomes through synergistic combinations of prebiotics, probiotics, and postbiotics, particularly in addressing specific health issues such as constipation, bacterial vaginosis, immune response, and gastrointestinal discomfort.
Innovation Solution
A nutritional composition comprising gold kiwifruit powder, Bacillus coagulans, and heat-treated Lactococcus lactis, formulated at specific weight ratios, administered in various forms for oral ingestion, to enhance gut health and immune function.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If existing nutritional compositions use single or dual components, then the formulation is simple, but the health outcomes are insufficient due to lack of synergistic effects
Solution Approach 1:
The patent combines three distinct biological components (prebiotics, probiotics, and postbiotics) into a single nutritional composition to achieve synergistic health benefits. This merging of multiple functional elements resolves the contradiction by creating a more effective formulation that addresses limitations of single or dual component approaches.
Solution Approach 2:
The invention creates a composite nutritional formulation integrating prebiotics (food for beneficial bacteria), probiotics (live beneficial bacteria), and postbiotics (metabolic byproducts of probiotics). This composite approach enhances health outcomes beyond what individual components can achieve alone, while maintaining a structured and manageable formulation.
2Reliability
If nutritional compositions lack synergistic combinations of prebiotics, probiotics, and postbiotics, then the formulation is simple, but specific health issues such as constipation, bacterial vaginosis, immune response, and gastrointestinal discomfort are not effectively addressed
Solution Approach 1:
The patent merges prebiotics, probiotics, and postbiotics into an integrated formulation that specifically targets multiple health conditions simultaneously. This combination approach resolves the contradiction by creating a multi-functional composition that addresses constipation, bacterial vaginosis, immune response, and gastrointestinal discomfort through synergistic interactions among the three component types.
3Reliability
If probiotics are administered without prebiotics and postbiotics, then the composition is simpler, but the probiotics may not survive digestion and reach the appropriate area of the digestive system in adequate amounts
Solution Approach 1:
The patent incorporates prebiotics into the formulation to prepare the digestive environment before probiotics need to survive and colonize. The prebiotics provide food sources that protect and nourish probiotics during digestion, ensuring their survival and effective delivery to target areas. This preliminary preparation resolves the contradiction by enhancing probiotic viability without overly complicating the formulation.
Solution Approach 2:
The prebiotics act as intermediaries that facilitate probiotic survival through the digestive system. By providing nutritional support and protective mechanisms, prebiotics mediate between the probiotics and the harsh digestive environment, enabling adequate probiotic delivery to the digestive tract. This intermediary role resolves the contradiction by improving probiotic survival while maintaining formulation simplicity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition significantly increases Faecalibacterium prausnitzii, reduces constipation symptoms, improves immune response, and alleviates gastrointestinal discomfort, while enhancing overall health and reducing inflammation and infection frequency.
Implementation Method 1
an amount of heat-treated Lactococcus lactis
Data Source
AI summary
Compositions including prebiotics, probiotics, and postbiotics for oral administration and methods of using such compositions for improving health of subjects are provided.