Precipitated Silica CPC Compatibility via Sodium Sulfate
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Solution Overview
Problem
Conventional silicas used in dentifrices tend to indiscriminately bind with cetylpyridinium chloride (CPC), reducing its antimicrobial effectiveness and causing flavor compatibility issues, leading to off-flavors and impaired functionality of both silica and CPC in oral care products.
Innovation Solution
Surface-modified silica particles are produced by incorporating sodium sulfate powder and high shear mixing during the manufacturing process, reducing pore sizes greater than 500 Å and enhancing CPC compatibility, allowing CPC to remain effective while maintaining silica's abrasive and flavor compatibility.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional silica is used as an abrasive in dentifrices, then silica's abrasive action is provided, but CPC adsorbs onto the silica surface reducing its antimicrobial effectiveness
Solution Approach 1:
The patent modifies the surface charge parameter of silica by adjusting pH and using surface treatment to transform the negatively charged surface into a positively charged or neutral surface, preventing CPC adsorption while maintaining abrasive functionality
Solution Approach 2:
The patent introduces an intermediary substance (such as a surfactant or coating agent) that modifies the silica surface properties, creating a barrier that prevents direct interaction between CPC and the silica surface
2Reliability
If conventional silica binds with CPC, then silica-CPC complex is formed, but flavor compatibility deteriorates causing off-flavors
Solution Approach 1:
The patent changes the surface charge parameter of silica to prevent binding with CPC, thereby eliminating the chemical interaction that causes off-flavors and improving overall flavor compatibility in the dentifrice formulation
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The modified silica particles achieve high CPC compatibility, ensuring CPC's antimicrobial efficacy and silica's abrasive action, while also providing superior flavor attributes and compatibility with fluoride ion sources, thus enhancing the performance of dentifrices.
Implementation Method 1
CPC adsorbs onto such conventional silica powders
Implementation Method 2
CPC is a cationic ('positively') charged compound... CPC's antimicrobial action is generally understood to result from its ability to bind to anionically ('negatively')-charged protein moieties
Implementation Method 3
Surface-modified silica particles are produced by incorporating sodium sulfate powder and high shear mixing during the manufacturing process, reducing pore sizes greater than 500 Å
Data Source
AI summary
Precipitated silica comprising porous silica particles having a cumulative surface area for all pores having diameters greater than 500 Å of less than 6 m2/g, as measured by mercury intrusion, and a percentage cetylpyridinium chloride (% CPC) Compatibility of greater than about 85%. The precipitated silica product is especially well-adapted for use in dentifrices containing cetylpyridinium chloride, which do not attach to the low surface area silica product in a meaningful level and thus remain available for antimicrobial action. Processes for making the silica product including the introduction of sodium sulfate powder during different process steps in order to enhance such a compatibility with CPC are provided.