Precision Dosing via Compound Extraction and Re-addition

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Solution Overview

Problem

Current methods for dosing psychedelics and cannabinoids in fungi and plants lack precision, leading to variable compound concentrations that can result in either ineffective microdosing or excessive substance intake, which affects functionality.

Innovation Solution

A method involving extraction of compounds from plant or fungi matter followed by precise addition of desired compounds to achieve a targeted concentration, utilizing techniques like liquid, chemical, or mechanical extraction, and testing to ensure accurate dosing, with the option to cross-breed compounds between different species or strains.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If natural plant or fungi matter is used with full spectrum compounds, then the entourage effect is achieved for enhanced potency, but the compound concentration varies widely making precise dosing difficult

Engineering Contradiction:

Improveentourage effectVSAvoidcompound concentration

Core Design Contradiction:

ReliabilityVSManufacturing precision

Solution Approach 1:

The invention segments the compound spectrum into two categories: full spectrum compounds (maintained for entourage effect) and specific active compounds (controlled for precision dosing). This allows the patent to preserve beneficial compound interactions while independently controlling the concentration of psychoactive substances through separate addition after extraction.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The patent changes the concentration parameter of specific active compounds independently from the full spectrum compounds. By extracting the full spectrum and then adding back controlled amounts of specific compounds, the system adjusts the concentration parameter to achieve both entourage effect and precise dosing requirements.

Inventive Principle:

Principle #35Parameter changes

2Reliability

If high concentration of compounds is present in natural product, then potency is maximized, but it does not lend well to microdosing and may affect functionality

Engineering Contradiction:

ImprovepotencyVSAvoidmicrodosing

Core Design Contradiction:

ReliabilityVSEase of operation

Solution Approach 1:

The patent applies partial action by extracting only a portion of the active compounds from the natural product rather than complete extraction. This leaves some compounds in the plant matter while removing enough to enable precise microdosing control, achieving the desired balance between maintaining potency and enabling safe, controlled dosing.

Inventive Principle:

Principle #16Partial or excessive action

Solution Approach 2:

The invention selectively extracts specific active compounds from the natural product while leaving the full spectrum matrix intact. This extraction allows for precise control over the amount of active compounds added back, enabling microdosing applications while preserving the entourage effect of the remaining natural compounds.

Inventive Principle:

Principle #2Taking out (Extraction)

3Manufacturing precision

If extraction and re-addition of compounds is performed, then precise dosing is achieved, but the process complexity increases

Engineering Contradiction:

Improvedosage accuracyVSAvoidprocess steps

Core Design Contradiction:

Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent performs preliminary extraction of the full spectrum compounds before adding back the specific active compounds in controlled amounts. This preliminary action of extraction creates a standardized base material that simplifies subsequent dosing operations, as the variable natural components are removed first and then systematically readded.

Inventive Principle:

Principle #10Preliminary action

Solution Approach 2:

The extraction process serves as an intermediary step that decouples the variable natural compound mixture from the controlled dosing requirement. By using extraction as a mediating process, the patent transforms an uncontrolled natural product into a controllable standardized material, simplifying the overall dosing operation despite the additional step.

Inventive Principle:

Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach ensures consistent and precise dosing, leveraging the 'entourage effect' of whole compounds for enhanced potency, while minimizing risks associated with excessive substance intake.

Implementation Method 1

extracting at least a portion of the compound concentration from the plant or fungi matter via an extraction method; in step (b), the extraction method is an extraction method selected from a liquid extraction, a chemical extraction, or a mechanical extraction

Methodology Applied

Scientific EffectLiquid extraction: Liquid-Liquid Extraction

Implementation Method 2

Methodology Applied

Scientific EffectChemical extraction: Solvation

Data Source

PatentUS11877986B1Method of precision dosing

Publication Date: 2024.01.23 TRUCELIUM INC

AI summary

Methods of precision dosing matter is provided. The matter, such as plant or fungi matter, include species having or lacking active mind alternating compounds. Various extraction methods are performed to remove these compounds, such that additional compounds of predetermined dosages may be added to the plant or fungi matter until a desired level of compound concentration is reached. Homogenizing and testing is carried out at various points to ensure accurate compound concentration levels.