Prefilled Liquid Cartridge for HPLC Solvent Supply
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Solution Overview
Problem
The handling of operating liquids in HPLC systems is cumbersome and hazardous due to the need for manual handling of open bottles above shoulder height, which can lead to tipping and contamination risks, especially with critical solvents.
Innovation Solution
A prefilled liquid cartridge system that allows for easy and safe connection to a sample separation device, featuring a liquid container prefilled with solvents and a secure liquid removal access, eliminating the need for manual filling and tube connections, and ensuring aseptic and standardized liquid supply.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If open bottles are used for storing operating liquids, then the liquid can be easily accessed, but the handling becomes cumbersome and hazardous when bottles are placed above shoulder height
Solution Approach 1:
The system divides the liquid storage function into separate modular cartridges that can be individually handled and inserted into the device at convenient heights, eliminating the need to handle large open bottles above shoulder height
Solution Approach 2:
The liquid is contained within a cartridge that is inserted into the device housing, creating a nested structure where the liquid container is protected within the device body, preventing tipping and spillage hazards
2Productivity
If tubes are manually connected to bottles for liquid supply, then the liquid flow can be controlled, but the tube handling becomes cumbersome and error-prone
Solution Approach 1:
The liquid conduit and cartridge are integrated into a single modular unit that is inserted as one piece into the device, combining the tube connection function with the liquid storage function and eliminating separate tube handling steps
Solution Approach 2:
The cartridge is designed with self-aligning features and automatic connection mechanisms that enable the liquid conduit to connect to the liquid source without manual intervention, allowing the system to self-establish the fluid connection
3Area of stationary object
If bottles are handled above shoulder height, then the device footprint is reduced, but the safety and hazard-free operation is compromised
Solution Approach 1:
The liquid cartridges are designed to be inserted horizontally or at ergonomic angles into the device rather than vertically from above, changing the dimensional approach to liquid loading and allowing safe handling at lower heights while maintaining compact device footprint
Data Source
AI summary
Prefilled liquid cartridge for fluidically connecting to a sample separation device for separating of components of a fluidic sample by using liquid of the liquid cartridge, wherein the liquid cartridge comprises a liquid container which is prefilled with liquid and a liquid removal access provided at the liquid container, adapted to be fluidically coupled with at least one liquid conduit of the sample separation device by only inserting the liquid cartridge in a corresponding liquid cartridge accommodation of the sample separation device.


