Preloaded Tissue Graft Cannula for Jam-Free MIS Delivery

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Solution Overview

Problem

Minimally invasive surgery (MIS) procedures face challenges with bone graft jamming during injection due to the need for manual loading into funnel or tubular devices, which is time-consuming and difficult, affecting surgical efficiency.

Innovation Solution

A cannula pre-loaded with a tissue graft, designed for minimally invasive surgery, that minimizes jamming by using a novel semi-automatic bone particulate loading device and method, maintaining viable bone cells and reducing extrusion resistance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If bone graft is manually loaded into funnel or tubular device on back table, then bone graft can be delivered to treatment site, but the process is time-consuming and bone graft frequently jams during injection

Engineering Contradiction:
Improvesurgical efficiencyVSAvoidtime for loading bone graft
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The cannula is pre-loaded with bone graft in a controlled environment before surgery. The bone graft is inserted into the cannula through a loading device that compresses and secures the graft material inside the cannula, eliminating the need for manual loading during the surgical procedure.

Inventive Principle:
Principle #10Preliminary action

2Reliability

If bone graft is manually loaded into funnel or tubular device, then bone graft can be delivered, but jamming occurs during injection process

Engineering Contradiction:
Improvesmooth delivery of bone graftVSAvoiddifficulty to overcome jamming
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The bone graft is pre-compressed and secured inside the cannula using a loading device before delivery. This preliminary compression ensures the graft is firmly held in position and prevents jamming during the injection process, as the graft is already compacted and cannot become dislodged or stuck.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

A loading device acts as an intermediary mechanism to compress and secure the bone graft inside the cannula. This device applies controlled compression forces to the graft material, ensuring it is firmly held in position and preventing jamming during delivery.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Strength

If high compression force is applied to tissue graft during loading, then graft is securely held in cannula, but extrusion force becomes too high causing damage

Engineering Contradiction:
Improveholding force of graft in cannulaVSAvoidextrusion force
Core Design Contradiction:
StrengthVSForce

Solution Approach 1:

The loading device applies controlled compression forces to the bone graft during loading, securing it firmly inside the cannula. The device is designed to apply sufficient compression to hold the graft securely while preventing excessive forces that could damage the graft or make extrusion impossible. The compression parameters are optimized to achieve the right balance.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS12471953B2Tissue graft delivery devices and uses thereof
Publication Date: 2025.11.18 LIFENET HEALTH
  • US12471953B2 patent drawing
  • US12471953B2 patent drawing
  • US12471953B2 patent drawing

AI summary

The present invention provides a cannula for delivering a tissue graft to a treatment site. The cannula comprises a distal end, a proximal end, a bore formed by an interior surface of the cannula, extending from the distal end to the proximal end and having a diameter, and a tissue graft inside the bore and in contact with the interior surface. The tissue graft may be released from the cannula at the distal end to the treatment site. The tissue graft may have a final loading pressure of 20-200 psi. Also provided is a delivery system comprising the cannula and a delivery device. Further provided are methods for delivering a tissue graft in a cannula to a treatment site and methods for preparing a cannula loaded with the tissue graft.