Preparative LC Management System for Error-Free Reinjection
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Solution Overview
Problem
The existing preparative liquid chromatograph systems require complex operations for registering injection and reinjection targets, leading to a high likelihood of setting errors.
Innovation Solution
A management system that allows users to register reinjection target containers directly on the fractionation result screen, without needing to open the injection registration screen, and enables designation of fractions to be reinjected on a chromatogram displayed on the fractionation result screen.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If the user opens the injection registration screen to register a container for reinjection, then the container can be registered as an injection target, but the operation becomes complicated and setting errors are likely to occur
Solution Approach 1:
The patent merges the reinjection registration function into the fractionation result screen, combining multiple functions (fractionation results display and reinjection target registration) into a single interface. This eliminates the need to switch between screens and reduces operational complexity while maintaining registration accuracy.
Solution Approach 2:
The fractionation result screen is designed to serve multiple purposes: displaying chromatogram data, showing fraction collection results, and enabling reinjection target container registration. This multi-functional design reduces the number of separate interfaces needed and simplifies the user workflow.
2Measurement precision
If the user checks the chromatogram and container position to identify the fraction for reinjection, then the correct fraction can be identified, but the operation time increases
Solution Approach 1:
The patent combines the chromatogram display, fraction collection position information, and container position mapping into a single integrated view on the fractionation result screen. This allows users to identify the correct fraction for reinjection by viewing all relevant information simultaneously rather than checking multiple separate sources, reducing operation time while maintaining identification accuracy.
Solution Approach 2:
The system pre-processes and displays the correspondence relationship between chromatogram positions and container positions before the user needs to perform reinjection. This preliminary organization of information allows for rapid identification of the target fraction without requiring the user to perform additional analysis or cross-referencing during the reinjection setup process.
Data Source
AI summary
A management system (1) for managing an operation of a preparative LC (100), the management system (1) including an injection registration part (2) configured to display an injection registration screen in response to a request from the user and register a container designated by the user on the injection registration screen as an injection target container, a result display part (6) configured to display a chromatogram created based on an output signal of a detector (108) of the preparative LC, create fractionation information indicating a correspondence relationship between a position on the chromatogram of each fraction collected in an individual container by a fractionator (112) of the preparative LC and a position of a container in which each fraction is collected, and display the created fractionation information as a fractionation result screen, a reinjection registration part (8) configured to allow the user to designate a fraction to be reinjected on the fractionation result screen, and configured to register a container in which the fraction designated by the user is collected as a reinjection target container when the fraction to be reinjected is designated by the user, and a controller (4) that controls operation of an injector of the preparative LC so that liquid contained in the container registered as the injection target container or the reinjection target container is injected.