Preservative Composition With Synergistic Broad-Spectrum Microbial Control

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Solution Overview

Problem

Existing antimicrobial agents used in products are harmful to human health and the environment, and there is a need for safer alternatives that effectively control bacteria, viruses, and dandruff-causing fungi while minimizing environmental impact.

Innovation Solution

A composition containing compounds represented by Formulas 1, 2, and 4, which exhibit synergistic antibacterial, antiviral, and antifungal effects, reducing the need for toxic chemicals like isothiazolinones and expensive agents like piroctone olamine and zinc pyrithione.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If isothiazolinone ingredients are used as preservatives, then antimicrobial effectiveness is improved, but human health safety deteriorates due to carcinogenic potential

Engineering Contradiction:
Improveantimicrobial effectivenessVSAvoidhuman health safety
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical parameters by replacing isothiazolinone ingredients with compounds having specific molecular structures (Formula 1: C7-C17 alkyl/alkenyl groups with hydroxyl or carboxyl terminals). This structural parameter change maintains antimicrobial effectiveness while eliminating carcinogenic properties, resolving the contradiction between reliability and safety

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs alternative preservative compounds that can be used at higher concentrations without long-term accumulation concerns, replacing the need for highly potent but toxic isothiazolinones. These alternative compounds achieve sufficient antimicrobial protection through their specific molecular structures without the harmful long-term effects

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Object-affected harmful factors

If antimicrobial agents are not used or weak antimicrobial property is used, then human health safety is improved, but product deterioration risk increases

Engineering Contradiction:
Improvehuman health safetyVSAvoidproduct stability
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent modifies the chemical parameters of preservative agents by using compounds with specific functional groups (hydroxyl, carboxyl) and carbon chain lengths (C7-C17). These parameter changes enable the use of milder preservatives that maintain product stability without the severe health risks associated with traditional strong antimicrobials

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs composite preservative systems combining multiple compounds with different mechanisms of action. This composite approach allows for reduced individual concentrations of each agent, maintaining overall product stability while minimizing health risks through synergistic effects

Inventive Principle:
Principle #40Composite materials

3Reliability

If piroctone olamine and zinc pyrithione are used for dandruff treatment, then antifungal effectiveness is improved, but product cost increases

Engineering Contradiction:
Improveantifungal effectivenessVSAvoidproduct cost
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent changes the chemical parameters by using compounds with specific structures (Formula 1 with C7-C17 chains) that naturally exhibit antifungal activity against Malassezia species. These structurally optimized compounds achieve comparable effectiveness to expensive agents like piroctone olamine and zinc pyrithione at lower costs

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs cost-effective alternative compounds that can be produced through simpler synthesis routes or obtained from natural sources. These compounds provide sufficient antifungal protection for dandruff treatment without the high manufacturing costs associated with patented molecules like piroctone olamine

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Data Source

PatentEP4659733A1Bactericidal and preservative composition
Publication Date: 2025.12.10 BJBIOCHEM CO LTD
  • EP4659733A1 patent drawing
  • EP4659733A1 patent drawing
  • EP4659733A1 patent drawing

AI summary

The present invention relates to an antibacterial, bactericidal, and preservative composition and a product containing same, the composition protecting, from microorganisms, the quality of products in various industrial fields including home care products such as clothes detergents, dish detergents, and household cleaning agents, personal care products such as shampoos, body cleansers, wet wipes, and cleansing products, and cosmetic products such as creams and emulsions. The antibacterial and preservative composition according to the present invention comprises a compound represented by chemical formula 1 and a compound represented by chemical formula 2, 3, or 4, thereby solving problems such as harmfulness to the human body and skin irritation, and enhancing antibacterial activity. In addition, an antidandruff hair care cosmetic composition or an antifungal composition, comprising the compound represented by chemical formula 1 of the present invention, has the effect of controlling dandruff-causing bacteria, and has a synergistic effect when the compound represented by chemical formula 1 is used together with a high-cost dandruff therapeutic agent, such as piroctone olamine, zinc pyrithione, or climbazole. In addition, an antiviral composition comprising the compound represented by chemical formula 1 of the present invention effectively controls microorganisms such as viruses and thus can be used as an ecofriendly infectious disease prevention composition for virus control.