Pressure-Equalization Filter Layout for Toxic Air Containment

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current pressure equalization mechanisms in closed system transfer devices (CSTDs) for CMR drugs fail to reliably prevent the escape of toxic air components during tests, such as TiCl4, due to insufficient filter performance, and often require excessive installation space.

Innovation Solution

A filter system with a main flow direction that is longer or equally long compared to other directions, arranged to maximize the flow path through the filter, ensuring sufficient filtration without increasing the installation space.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the filter is arranged with the main flow direction perpendicular to the filter membrane surface (shortest path), then the installation space is minimized, but the filtration performance is insufficient to prevent toxic substance escape

Engineering Contradiction:
Improvefiltration performanceVSAvoidfilter extension in main flow direction
Core Design Contradiction:
ReliabilityVSLength of stationary object

Solution Approach 1:

The filter is rotated 90 degrees relative to the conventional arrangement, changing the dimension in which the flow path extends. Instead of the flow path being perpendicular to the filter surface (shortest path), the main flow direction is now along the longer extension of the filter, utilizing the length dimension to extend the flow path and improve filtration performance without increasing the cross-sectional area.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Reliability

If the filter extension in the main flow direction is increased to improve filtration, then the filtration performance improves, but the installation space increases

Engineering Contradiction:
Improvefiltration performanceVSAvoidinstallation space
Core Design Contradiction:
ReliabilityVSArea of stationary object

Solution Approach 1:

The solution utilizes the length dimension of the filter housing to extend the flow path, rather than increasing the cross-sectional area. By arranging the main flow direction along the longer extension of the filter and rotating the filter 90 degrees, the invention achieves extended flow path length without increasing the installation footprint, effectively using the third dimension (length) to resolve the space-performance contradiction.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The filter system effectively prevents the escape of toxic substances during tests and maintains high filtration efficiency with the same or reduced space, passing standardized smoke tests and ensuring no substances escape to the outside.

Implementation Method 1

pressure equalization is achieved, for example, by means of a hydrophobic filter membrane and a further filter made of activated carbon fabric connected in series

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 2

pressure equalization is achieved, for example, by means of a hydrophobic filter membrane

Methodology Applied
Scientific EffectHydrophobicity: Hydrophobe

Implementation Method 3

a further filter made of activated carbon fabric connected in series

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentUS20250339343A1Filter system for a closed fluid-transfer system with pressure equalization
Publication Date: 2025.11.06 B BRAUN MELSUNGEN AG
  • US20250339343A1 patent drawing
  • US20250339343A1 patent drawing
  • US20250339343A1 patent drawing

AI summary

A filter system for a closed fluid transfer system with pressure equalization. The filter system includes a filter having a main flow direction for a fluid passing through the filter extending from a fluid inlet surface to a fluid outlet surface, and a filter housing. The filter has a greater or at least equal extension in the main flow direction compared to at least one direction transverse to the main flow direction.