Pressure-Responsive Infusion Hose for Local Fluid Delivery
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Solution Overview
Problem
Existing medical fluid administration devices lack flexibility and adaptability, are limited in active ingredient modification, and cause tissue irritation due to fixed dimensions and diffusion-based release, leading to ineffective treatment of infections and implant disinfection.
Innovation Solution
A deformable hose with dual-material walls and pressure-responsive orifices allows for adjustable length and continuous, localized delivery of medical fluids, preventing tissue irritation and enabling replacement of active ingredients.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If diffusion-based active ingredient release is used, then large quantities of active ingredient can be released in the first few hours or days, but the active ingredient can no longer be replaced or supplemented by other active ingredients after implantation
Solution Approach 1:
The device segments the active ingredient delivery system into multiple interchangeable cartridges, each containing different active ingredients. The injection needle assembly can be detached and replaced with different cartridges, allowing the medical user to switch between different antibiotics or pharmaceutical agents based on treatment requirements and microbial sensitivity patterns.
Solution Approach 2:
The system transitions from a static, fixed-composition bead chain to a dynamic system where the active ingredient cartridge can be exchanged during treatment. This allows adaptation to changing clinical conditions, such as when microbial sensitivity results become available or when treatment failure occurs, enabling supplementation or replacement of active ingredients without removing the entire device.
2Ease of manufacture
If fixed-dimension devices are used, then manufacturing is simplified, but the device cannot be adapted to different anatomical situations or cavity sizes
Solution Approach 1:
The device is divided into modular segments including the injection needle assembly, the cartridge containing the active ingredient, and the hub portion. The cartridge can be exchanged while keeping the injection needle and hub in place, providing adaptability to different treatment scenarios without requiring complete device replacement or complex custom manufacturing.
Solution Approach 2:
The injection needle assembly and hub portion serve as universal components that can accommodate different cartridge types and configurations. This universal interface allows a single base device to be used across multiple anatomical sites and treatment scenarios by simply changing the cartridge, eliminating the need for multiple fixed-dimension device variants.
3Duration of action of moving object
If bead chains are implanted for long-term active ingredient release, then treatment duration is extended, but removal is associated with considerable stress for the patient due to intergrowth with connective tissue
Solution Approach 1:
The active ingredient cartridge is designed as a separable component that can be extracted from the injection needle assembly without removing the entire device from the patient's body. When treatment is complete or adjustment is needed, only the cartridge containing the active ingredient beads needs to be withdrawn and replaced, leaving the injection needle and hub in place, thereby minimizing tissue disruption and patient stress.
Solution Approach 2:
The cartridge containing the active ingredient beads is designed as a disposable, single-use component. After the active ingredient is depleted or treatment is complete, the cartridge is discarded and replaced rather than attempting to remove or clean it. This approach eliminates the removal stress associated with long-term implanted devices while maintaining effective treatment duration through sequential cartridge changes.
4Duration of action of moving object
If non-absorbable active ingredient vehicles like PMMA beads are used, then the active ingredient can be released over several days, but the vehicle cannot be modified with further antibiotics according to microbial sensitivity
Solution Approach 1:
The active ingredient delivery system is segmented into the reusable injection needle assembly and the replaceable cartridge containing the PMMA beads. This segmentation allows the cartridge to be exchanged based on microbial sensitivity results, enabling switching between different antibiotics while maintaining the benefit of sustained release from the PMMA bead matrix.
Solution Approach 2:
The system allows changing the chemical parameter (type of antibiotic) by replacing the cartridge while maintaining the physical parameter (sustained release mechanism) of the PMMA beads. Different cartridges can contain PMMA beads loaded with different antibiotics or antibiotic combinations, enabling adaptation to changing microbial sensitivity patterns without altering the effective delivery mechanism.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device provides flexible, continuous, and adjustable administration of medical fluids, reducing tissue irritation and enabling precise control over active ingredient concentration and delivery duration without complex systems.
Implementation Method 1
The hose wall has an outer wall of a first material which is arranged radially to the outside, and the hose wall has an inner wall of a second material which is arranged radially to the inside... the multiple orifices can be opened through the pressure of a medical fluid acting on the multiple orifices
Data Source
AI summary
One aspect relates to a device for local administration of a medical fluid having a hose which is flexibly deformable and has a hose wall. The hose wall has a first material, and a second material, which is different than the first material. In a distal portion of the hose, the hose has multiple orifices in the hose wall. The multiple orifices connect the inner conduit with the surroundings of the hose. The distal portion has a distal end. The device has a closing element that is insertable into the distal end of the hose. A proximal end of the hose is connectable with a container for the medical fluid such that the medical fluid is able to be forced out of the container through the proximal end of the hose into the inner conduit of the hose and forced through the multiple orifices to the surroundings of the hose.