Pressure-Sensing Nasal Cannula for Real-Time Oxygen Titration

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Solution Overview

Problem

Existing oxygen delivery systems lack real-time adjustment capabilities based on patient inspiratory flow rates, leading to insufficient or excessive oxygen delivery, which can cause discomfort, lung damage, and inefficiencies in nebulized drug delivery.

Innovation Solution

A nasal cannula system with integrated pressure sensors and a controller that measures inspiratory flow rates, tidal volume, and minute ventilation to automatically adjust oxygen flow rates and concentrations in real-time, matching patient demands.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If high flow delivery systems are used to provide gas flow of up to 60 L per minute, then oxygen delivery capability is improved, but the flow rates are set arbitrarily without real time knowledge of patient's inspiratory flow rates, leading to excessive oxygen delivery

Engineering Contradiction:
Improveoxygen delivery capabilityVSAvoidlack of real-time knowledge of patient's inspiratory flow rates
Core Design Contradiction:
Quantity of substanceVSLoss of information

Solution Approach 1:

The system incorporates a flow sensor that continuously monitors the patient's inspiratory flow rate and provides real-time feedback to the controller. The controller automatically adjusts the oxygen flow rate based on this feedback, ensuring the delivered oxygen matches the patient's actual respiratory demand. This closed-loop feedback mechanism eliminates arbitrary flow rate setting and prevents both insufficient and excessive oxygen delivery.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system enables the patient to effectively control their own oxygen delivery through their natural breathing pattern. The flow sensor detects the patient's inspiratory flow, and the system automatically adjusts accordingly, allowing the patient's physiological needs to drive the therapy without requiring manual intervention or arbitrary provider decisions.

Inventive Principle:
Principle #25Self-service

2Reliability

If flow rate is increased to avoid insufficient oxygen delivery, then oxygen supply adequacy is improved, but discomfort to the patient occurs due to large amounts of oxygen flow hitting the nasal mucus membranes

Engineering Contradiction:
Improveoxygen supply adequacyVSAvoiddiscomfort to patient from large amounts of oxygen flow
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The real-time flow monitoring provides continuous feedback on the patient's actual oxygen needs. The system adjusts the flow rate to match demand precisely, delivering sufficient oxygen to maintain adequate supply while avoiding excessive flow that would cause discomfort to nasal mucus membranes. This dynamic adjustment prevents both hypoxia and flow-related discomfort.

Inventive Principle:
Principle #23Feedback

3Adaptability or versatility

If manual titration of oxygen is performed by providers increasing flow rates at set time intervals, then oxygen delivery can be adjusted, but the process is laborious and resources are strained

Engineering Contradiction:
Improveoxygen delivery adjustment capabilityVSAvoidlaborious process involving manual adjustments at set time intervals
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The system performs automatic titration of oxygen flow rates without requiring manual intervention by healthcare providers. The flow sensor continuously monitors patient demand, and the controller automatically adjusts the flow rate in real-time based on detected inspiratory flow patterns. This eliminates the laborious manual titration process and frees up provider resources while maintaining precise oxygen delivery adjustment capability.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The manual mechanical process of provider adjustment is replaced with an automated electronic control system. The flow sensor and controller work together to automatically regulate oxygen flow, substituting the manual titration mechanism with an electronic feedback-based adjustment system that operates continuously without human intervention.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Reliability

If flow rate is set higher than needed, then risk of insufficient oxygen delivery is avoided, but waste of oxygen occurs and cost increases

Engineering Contradiction:
Improveprevention of insufficient oxygen deliveryVSAvoidwaste of oxygen
Core Design Contradiction:
ReliabilityVSLoss of energy

Solution Approach 1:

The continuous flow monitoring provides real-time feedback on actual patient oxygen consumption. The system adjusts the delivered flow to match this consumption precisely, ensuring sufficient oxygen delivery is maintained while eliminating the waste associated with setting flow rates higher than needed. This feedback-driven precision delivery optimizes both safety and resource utilization.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system dynamically changes the oxygen flow rate parameter based on real-time detection of patient inspiratory flow. By continuously adjusting this parameter to match actual demand rather than maintaining a fixed high setting, the system prevents insufficient delivery while minimizing oxygen waste and associated costs.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system ensures optimal oxygen delivery, reducing discomfort, minimizing lung damage, enhancing nebulized medication delivery, and improving treatment outcomes by accurately matching gas flow to patient needs.

Implementation Method 1

A side wall of the nasal prong defines a port at the second end portion of the nasal prong and in fluid communication with the flow passage. The port is configured to be fluidically coupled to a pressure sensor such that a series of pressure measurements within the flow passage of the nasal prong can be taken over a period of time during the delivery of the flow of the oxygen-containing gas.

Methodology Applied
Scientific EffectPressure measurement:

Data Source

PatentUS20250332368A1System, devices and methods for delivering a flow of oxygen
Publication Date: 2025.10.30 VIRGINIA TECH INTELLECTUAL PROPERTIES INC
  • US20250332368A1 patent drawing
  • US20250332368A1 patent drawing
  • US20250332368A1 patent drawing

AI summary

An apparatus includes a nasal cannula having a nasal prong. The nasal prong includes a first end portion that defines an inlet opening, a second end portion that defines an outlet opening, and a middle portion. A side wall of the nasal prong defines a flow passage between the inlet opening and the outlet opening. The nasal prong is configured to be inserted within a nostril of a patient with the outlet opening disposed within the nostril. The inlet opening is fluidically coupled to a support tube to deliver a flow of the gas into the airway of the patient via the nasal prong. The side wall of the nasal prong defines a port that is in fluid communication with the flow passage. The port is fluidically coupled to a pressure sensor to take a series of pressure measurements within the flow passage during the delivery of the oxygen-containing gas.