Pressurized Catheter Agent Delivery for Deep GI Tissue Dosing
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Solution Overview
Problem
Current medical systems for delivering pressurized fluids or agents during endoscopic procedures face challenges such as complex delivery mechanisms, inconsistent dosing, clogging issues, and difficulty in reaching deep tissue sites within the gastrointestinal tract.
Innovation Solution
A device comprising a catheter with a lumen, an enclosure for storing the agent and receiving pressurized fluid, and a valve system that allows controlled release of the fluid and agent combination, enabling precise delivery to a target tissue site.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If mechanical agent delivery systems are used, then agent delivery can be achieved, but the systems require numerous steps or actuations and have complex delivery mechanisms
Solution Approach 1:
The patent extracts the pressurized fluid delivery system from the traditional mechanical actuation system. A separate pressurized fluid container delivers fluid through a fluid input to the enclosure, replacing complex mechanical actuation steps with a simpler fluid-pressure-based delivery mechanism. This reduces the number of steps or actuations required while maintaining effective agent delivery capability.
2Productivity
If traditional agent delivery systems are used, then agent delivery is possible, but the systems may not achieve desired rate of agent delivery or desired dosage
Solution Approach 1:
The patent incorporates a valve system that responds to pressure conditions within the enclosure to control agent release. The valve opens in response to pressure from the pressurized fluid and closes when pressure equalizes, providing automatic feedback control. This ensures consistent dosing and achieves the desired rate of agent delivery without requiring complex external control mechanisms.
3Productivity
If mechanical delivery systems are used, then agent can be delivered, but the agent may clog portions of the delivery device
Solution Approach 1:
The patent uses pressurized fluid to deliver the agent through the catheter and into the enclosure, replacing mechanical pushing mechanisms. The fluid pressure smoothly propels the agent through the delivery system, reducing friction and contact points where clogging could occur. This hydraulic approach maintains reliable agent delivery while minimizing clogging risks.
4Length of moving object
If traditional delivery methods are used, then agent delivery is possible, but the agent may not reach treatment site deep within GI tract
Solution Approach 1:
The patent employs pressurized fluid to propel the agent through the catheter and into the enclosure, generating the necessary force to reach deep treatment sites within the GI tract. The pressurized fluid system can deliver agent with sufficient force and pressure to overcome the distance and resistance encountered in deep tissue delivery, achieving effective treatment at remote locations.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution provides a simplified, efficient, and controlled method for delivering agents to deep tissue sites within the GI tract, reducing the risk of clogging and ensuring consistent dosing.
Implementation Method 1
A first fluid input may be configured to release pressurized fluid from a pressurized fluid container into the lumen upon coupling the container to the first fluid input
Implementation Method 2
The valve may also include a biasing member coupled to the rod, and the biasing member may be configured to bias the rod towards the first configuration of the valve
Data Source
AI summary
A device may be configured to deliver an agent to a target tissue via a pressurized fluid and the device may include a catheter including a lumen; an enclosure configured to store the agent, receive the pressurized fluid, and release a combination of the pressurized fluid and the agent; and a valve downstream of the enclosure to receive the combination of the pressurized fluid and the agent from the enclosure. The valve may have a first configuration preventing a flow of the combination through the lumen and a second configuration permitting the flow of the combination through the lumen.