Pressurized Gas Injection Device for High Viscosity Medicament Delivery
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Solution Overview
Problem
Existing automatic medicament delivery devices face challenges with high viscosity and large volume liquid medicaments, leading to patient discomfort and inefficiencies, particularly in terms of injection time and needle handling, and require improved force delivery and user-friendly operation.
Innovation Solution
An injection device with a pressurized fluid system that precisely displaces both the medicament reservoir and injection needle, providing a high dispensing force, tactile and audible feedback, and automatic needle extension and retraction, while being lightweight and cost-efficient for mass production.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Extent of automation
If a compressed gas cylinder is used to displace the medicament container, then the injection needle can be extended and retracted automatically, but the housing requires robust construction and precise geometry which increases device complexity
Solution Approach 1:
The patent uses a pressurized gas reservoir to provide pneumatic force for displacing the medicament container and driving the injection mechanism. The gas pressure acts on a piston or diaphragm to convert pneumatic energy into mechanical motion, enabling automatic needle extension and retraction without complex mechanical linkages
Solution Approach 2:
The device is divided into functional modules: a pressurized gas reservoir, a medicament container, a needle assembly, and a control mechanism. Each module operates semi-independently, allowing simplified design of individual components while maintaining overall automated functionality
2Device complexity
If existing drug delivery devices are used for high viscosity and large volume medicaments, then the device structure is simple, but the injection time exceeds predefined ranges and causes patient discomfort
Solution Approach 1:
The medicament container is pre-loaded into the device before activation. The pressurized gas system is pre-configured to deliver the required force. When activated, the device immediately begins dispensing without requiring manual assembly or preparation, reducing total injection time
Solution Approach 2:
The device applies controlled pressure parameters to the high viscosity medicament to maintain flow within acceptable time ranges. The pressurized gas system dynamically adjusts force application to optimize dispensing rate for viscous formulations without compromising patient comfort
3Extent of automation
If the pressurized gas cylinder is displaced from first position to second position, then medicament delivery is activated, but gas tight coupling requires precise geometry increasing manufacturing difficulty
Solution Approach 1:
The patent employs flexible sealing elements such as elastomeric diaphragms or O-rings to achieve gas-tight coupling. These flexible components compensate for minor geometric variations in the housing and cylinder interfaces, maintaining sealing integrity without requiring ultra-precise manufacturing tolerances
Solution Approach 2:
A flexible membrane or sealing intermediary is introduced between the pressurized gas cylinder and the housing to create the gas-tight barrier. This intermediary element absorbs dimensional variations and ensures reliable sealing while simplifying the geometric requirements of the rigid components
Data Source
AI summary
The present invention relates to an injection device for dispensing of a liquid medicament, the device comprising: a base (10), a medicament reservoir (20) displaceably arranged on the base (10) and containing the liquid medicament (25), an injection needle (30) displaceably arranged relative to the base (10) between a retracted position (30a) and an extended position (30b), a pressure container (40) containing a pressurized fluid (24), a reservoir displacing arrangement (50) coupled with the pressure container (40) to displace the medicament reservoir (20) into a dispensing position (20b), in which the medicament reservoir (20) is in fluid communication with the injection needle (30), a needle displacing arrangement (60) coupled with the pressure container (40) to at least displace the injection needle (30) into the extended position (30b).