Pressurizing Assembly for Rapid Whole Blood Testing
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Solution Overview
Problem
Current rapid screening tests in the medical field require complex pre-processing of whole blood samples, which is time-consuming and costly, limiting their efficiency.
Innovation Solution
A test apparatus with a pressurizing assembly that includes a detachable base and pressurizing member forming a sample chamber, which applies pressure to a liquid sample to enter a test strip, potentially using a filter film and reaction layer to filter and react with the sample, eliminating the need for pre-processing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Speed
If a rapid screening test is performed using plasma or serum samples, then the test speed is improved, but complicated pre-processing is required to obtain plasma or serum from whole blood
Solution Approach 1:
The device segments the testing process into distinct functional zones within the test strip: a sample collection region that receives whole blood, a reaction region where the actual test occurs, and intermediate zones for sample preparation. This segmentation allows whole blood to be directly applied without external pre-processing equipment.
Solution Approach 2:
The test strip acts as an intermediary device that performs the pre-processing functions internally. It includes integrated components such as sample collection structures, reaction chambers, and detection elements that collectively transform whole blood into a test-ready state without requiring external processing equipment.
2Measurement precision
If complicated pre-processing is performed on whole blood samples to obtain plasma or serum, then the test accuracy is improved, but the testing time and cost increase
Solution Approach 1:
The test strip incorporates preliminary action features directly into its structure, including pre-formed reaction chambers, pre-loaded reagents, and pre-configured sample collection areas. When whole blood is applied, these pre-prepared components immediately begin the separation and reaction processes, eliminating the need for separate pre-processing steps.
Solution Approach 2:
The device merges multiple functions (sample collection, separation, reaction, and detection) into a single integrated test strip. This consolidation allows the entire process from whole blood application to result generation to occur in one device without transferring samples between multiple processing stations.
3Productivity
If a pressurizing assembly is added to the test apparatus, then the sample processing capability is improved, but the device complexity increases
Solution Approach 1:
The pressurizing assembly is designed with multi-functionality to justify its addition: it can actively propel samples through the test strip when rapid processing is needed, while also allowing passive sample application when the button is not pressed. This dual capability provides productivity enhancement without forcing complexity in all usage scenarios.
Solution Approach 2:
The pressurizing mechanism introduces dynamic control to the otherwise static test strip system. The button-activated pressurizing member can be engaged or disengaged based on testing needs, providing on-demand sample propulsion capability that enhances processing speed without permanently complicating the device structure.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables rapid and convenient testing by directly processing whole blood samples without pre-treatment, saving time and cost while providing accurate results through the pressurizing assembly's ability to filter and react with the sample.
Implementation Method 1
the pressurizing member is adapted to exert the pressure to the liquid sample, such that the liquid sample enters the sample collecting region
Implementation Method 2
the pressurizing assembly further includes a filter film disposed between the base and the cassette main body, and separating the sample entrance and the sample chamber
Implementation Method 3
the reaction layer covering the sample collecting region and configured to have a chemical reaction with the liquid sample
Data Source
AI summary
A test apparatus including a cassette main body, a test strip and a pressurizing assembly is provided. The cassette main body has a sample entrance. The test strip is disposed in the cassette main body, and the sample entrance of the cassette main body exposes a sample collecting region of the test strip. The pressurizing assembly is detachably combined to the cassette main body, and is adapted to exert a pressure on a liquid sample located at the sample entrance, such that the liquid sample enters the sample collecting region, and reacts with the test strip to display a test result. The test apparatus is able to implement quick and convenience test, by which a complicated pre-processing of a test sample is omitted to save a time and test cost.