Personalized Nutrient Composition via Printed Dosage Forms

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Solution Overview

Problem

Current nutritional supplementation methods fail to provide personalized and tailored nutrient intake, leading to deficiencies or excesses, which can adversely affect health, especially in vulnerable populations such as hospital and nursing home patients.

Innovation Solution

A nutritional composition, preferably printed using inkjet or 3D printing technologies, is developed with specific nutrient levels tailored to individual needs, administered through units like tablets, foils, or films designed for easy oral absorption, ensuring the right amount of nutrients is delivered based on calculated target and actual intake values.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If routine supplementation of critical nutrients is provided to all patients, then nutrient deficiencies are prevented, but excessive intake of certain nutrients may lead to hypervitaminosis and thyroid dysfunction

Engineering Contradiction:
Improveprevention of nutrient deficienciesVSAvoidadverse effects from excessive nutrient intake
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies local quality by customizing nutrient supplementation for each individual patient based on their specific nutrient status, dietary intake, and clinical condition. Instead of uniform supplementation, the system determines personalized target values for each nutrient and calculates the precise difference that needs to be compensated, ensuring each patient receives exactly what they need without excess

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent implements dynamics by making nutrient supplementation adaptive and adjustable. The system continuously monitors patient progress, recalculates nutrient requirements based on changing clinical conditions and actual intake, and adjusts supplementation levels accordingly. This dynamic approach allows the supplementation regimen to evolve with the patient's needs over time

Inventive Principle:
Principle #15Dynamics

2Object-affected harmful factors

If personalized nutritional supplementation is implemented, then adverse effects from excessive intake are prevented, but complexity in determining and administering precise nutrient doses increases

Engineering Contradiction:
Improveadverse effects from excessive nutrient intakeVSAvoidcomplexity in personalized supplementation system
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent applies feedback by systematically collecting data on patient nutrient status through laboratory tests, monitoring actual dietary intake, and tracking supplementation administration. This feedback loop enables continuous calculation of the difference between target and actual nutrient levels, allowing the system to dynamically adjust supplementation recommendations and ensure patients receive precise, personalized doses

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent implements self-service by enabling the system to automatically calculate personalized supplementation requirements based on input data from nutrient status assessments and dietary records. The system autonomously determines target values, computes the difference that needs compensation, and generates individualized supplementation regimens without requiring manual intervention for each calculation

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS10537129B2Personalized supplementation of nutrients
Publication Date: 2020.01.21 SOCIETE DES PRODUITS NESTLE SA
  • US10537129B2 patent drawing

AI summary

The present invention provides nutritional compositions, preferably printed, comprising at least one nutrient for which a deficiency in nutrient intake and/or nutrient status in a subject was detected. Such nutritional composition is comprised by an administration unit, and the nutrient is present at an amount corresponding to the difference between the target value and actual value of the nutrient intake and/or status in the subject. The invention further provides medical uses of such printed nutritional compositions, e.g. in the treatment or prophylaxis of malnutrition. The invention also provides administration units comprising such the nutritional compositions, as well as a system and method for producing the same.