Prior-Image Reconstruction Decomposition for Feature Attribution

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Solution Overview

Problem

Advanced tomographic reconstruction methods often disregard valuable patient-specific prior information, leading to suboptimal image quality and increased radiation dose, especially in scenarios where prior imaging data can significantly contribute to the understanding of patient anatomy.

Innovation Solution

A novel framework that decomposes the estimation of image features into components supported by current and prior data, allowing for a spatial map to quantify contributions and trace features to their source, thereby enhancing the representation of image features and adjusting the strength of prior information in the reconstruction.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If prior image-based reconstruction methods are used, then data fidelity requirements are reduced and undersampling is accommodated, but accurate representation of image features becomes compromised

Engineering Contradiction:
Improvedata fidelity requirementsVSAvoidimage feature representation accuracy
Core Design Contradiction:
Measurement precisionVSManufacturing precision

Solution Approach 1:

The patent segments the image reconstruction into distinct components: a first component derived from current projection data and a second component derived from prior images. This segmentation allows independent optimization of each component's contribution, enabling accurate feature representation while reducing data fidelity requirements through controlled integration of prior information.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies local quality by differentiating the treatment of different image regions through the decomposition framework. By analyzing the contribution of prior images versus current data at different spatial locations, the method can selectively weight prior information where appropriate while maintaining data-driven accuracy where current measurements are reliable, thus resolving the contradiction between reduced data requirements and feature accuracy.

Inventive Principle:
Principle #3Local quality

2Productivity

If prior information is incorporated into reconstruction, then imaging speed is improved and radiation dose is reduced, but the source of image features becomes ambiguous

Engineering Contradiction:
Improveimaging speedVSAvoidfeature source attribution
Core Design Contradiction:
ProductivityVSLoss of information

Solution Approach 1:

The patent implements feedback through the decomposition framework that quantifies and tracks the contribution of prior images versus current data to the final reconstruction. This feedback mechanism provides transparency about feature origins, allowing users to understand which features arise from prior information and which from current measurements, thus resolving the ambiguity while maintaining the speed and dose benefits.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent introduces an intermediary decomposition framework that mediates between prior image information and current projection data. This intermediary layer systematically combines both sources while attributing features to their respective origins, enabling fast reconstruction with reduced radiation dose while maintaining clear knowledge of feature sources through the quantitative contribution analysis.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Device complexity

If general notions of local smoothness are used, then reconstruction is simplified, but patient-specific prior information is disregarded

Engineering Contradiction:
Improvereconstruction method complexityVSAvoidpatient-specific prior information
Core Design Contradiction:
Device complexityVSLoss of information

Solution Approach 1:

The patent merges the simplicity of general smoothness constraints with the specificity of patient prior information through the decomposition framework. The first component captures general smoothness characteristics while the second component incorporates patient-specific prior information, combining both approaches to achieve simple yet personalized reconstruction that respects individual anatomical variations.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent applies preliminary action by incorporating prior image information before the final reconstruction is completed. By pre-processing and integrating patient-specific prior knowledge into the reconstruction framework, the method simplifies the overall reconstruction process while preserving individual anatomical characteristics, avoiding the need for complex iterative optimization from scratch.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS9626778B2Information propagation in prior-image-based reconstruction
Publication Date: 2017.04.18 JOHNS HOPKINS UNIVERSITY
  • US9626778B2 patent drawing
  • US9626778B2 patent drawing
  • US9626778B2 patent drawing

AI summary

A framework, comprising techniques, process(es), device(s), system(s), combinations thereof, or the like, to analyze propagation of information in prior-image-based reconstruction by decomposing the estimation into distinct components supported by a current data acquisition and by a prior image. Such decomposition can quantify contributions from prior data and current data as a spatial map and/or can trace specific features in an image to a source of at least some of such features.