Probabilistic Motion Model for Medical Image Deformation

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Solution Overview

Problem

Conventional motion analysis in medical imaging struggles to extract consistent temporal deformations and intrinsic motion parameters, leading to difficulties in modeling and understanding organ motion patterns, with existing registration algorithms lacking realism and personalization.

Innovation Solution

A machine learning-based probabilistic motion model is employed, comprising an encoding network, temporal convolutional network, and decoding network, to learn a motion representation that captures underlying motion features in medical image sequences, enabling deformation field calculation, motion simulation, interpolation, and extrapolation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional registration algorithms with temporal regularization are used, then accurate deformation fields are produced, but intrinsic motion parameters cannot be extracted

Engineering Contradiction:
Improvedeformation field accuracyVSAvoidintrinsic motion parameters
Core Design Contradiction:
Measurement precisionVSLoss of information

Solution Approach 1:

The patent extracts intrinsic motion parameters from the deformation field by introducing a motion parameter extraction module that identifies and isolates meaningful motion characteristics (such as organ contraction, expansion, or translation) from the computed deformation field, separating essential motion information from noise and artifacts

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces an intermediate motion parameter representation layer between the image registration process and the final deformation field output. This intermediate layer captures intrinsic motion parameters that serve as a bridge, allowing both accurate deformation computation and meaningful motion characterization to coexist

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If biomechanical models are used to model motion, then motion patterns can be characterized, but realism and personalization are compromised

Engineering Contradiction:
Improvemotion pattern characterizationVSAvoidrealism and personalization
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent employs a dynamic, data-driven motion model that adapts to individual subjects based on their specific image sequences. Rather than using fixed biomechanical assumptions, the model learns motion patterns directly from the subject's own imaging data, enabling personalization while maintaining physical plausibility through regularization constraints

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent changes the fundamental parameters of the motion model from fixed biomechanical constants to subject-specific parameters learned from imaging data. This allows the model to capture individual anatomical variations and motion characteristics while maintaining the mathematical framework needed for realistic motion simulation

Inventive Principle:
Principle #35Parameter changes

3Loss of information

If machine learning based motion model is used, then intrinsic motion parameters are extracted and temporal consistency is improved, but computational complexity increases

Engineering Contradiction:
Improveintrinsic motion parameters extractionVSAvoidcomputational complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The patent segments the computational process into distinct modular components: image registration module, deformation field computation module, motion parameter extraction module, and synthesis module. Each module handles a specific aspect of the computation, allowing for optimized processing and reducing overall computational complexity through specialized algorithms in each segment

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS11403761B2Probabilistic motion model for generating medical images or medical image sequences
Publication Date: 2022.08.02 SIEMENS HEALTHINEERS AG
  • US11403761B2 patent drawing
  • US11403761B2 patent drawing
  • US11403761B2 patent drawing

AI summary

Systems and methods for performing a medical imaging analysis task using a machine learning based motion model are provided. One or more medical images of an anatomical structure are received. One or more feature vectors are determined. The one or more feature vectors are mapped to one or more motion vectors using the machine learning based motion model. One or more deformation fields representing motion of the anatomical structure are determined based on the one or more motion vectors and at least one of the one or more medical images. A medical imaging analysis task is performed using the one or more deformation fields.