High-Probability Differential Diagnosis Generator With Bayesian Ranking

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Solution Overview

Problem

Traditional diagnostic approaches rely on subjective judgment and often overlook important clinical information, leading to potential errors and inefficiencies in patient care.

Innovation Solution

An artificial intelligence system integrating Ockham's Razor and Bayesian Theorem to generate high and low probability differential diagnoses based on patient data, symptoms, and clinical findings, assisting healthcare providers in accurate diagnosis and reducing errors.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional diagnostic approaches are used, then ease of operation is maintained, but diagnostic accuracy deteriorates due to subjective judgment and overlooked clinical information

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

An AI-based diagnostic support system serves as an intermediary between healthcare providers and patient data. The system processes clinical information, applies Bayesian Theorem and Ockham's Razor algorithms, and generates differential diagnoses to assist providers, thereby improving diagnostic accuracy without replacing human judgment.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces subjective mechanical diagnostic processes with an automated AI system that uses mathematical frameworks (Bayesian Theorem for probability calculation and Ockham's Razor for simplicity principle) to objectively analyze clinical data and generate ranked differential diagnoses.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If comprehensive clinical information is collected, then diagnostic accuracy is improved, but time consumption increases

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidtime consumption
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary analysis of clinical information by automatically processing and storing patient data, signs, symptoms, and clinical findings before the diagnostic process. This pre-processing enables rapid retrieval and analysis during actual diagnosis, reducing time consumption while maintaining comprehensive information collection.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The AI system provides feedback by generating ranked differential diagnoses based on the collected clinical information. This feedback loop allows healthcare providers to quickly review and adjust their diagnostic approach, efficiently utilizing the comprehensive data without excessive time expenditure.

Inventive Principle:
Principle #23Feedback

3Measurement precision

If multiple diagnostic hypotheses are generated, then diagnostic accuracy is improved, but device complexity increases

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidalgorithm complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system changes parameters by dynamically adjusting the number and ranking of diagnostic hypotheses based on the complexity of the clinical presentation. Using Bayesian Theorem, the system calculates probability scores and generates an appropriate number of differential diagnoses (e.g., top 3-5 most likely conditions), balancing comprehensive analysis with computational efficiency.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The AI system applies partial action by generating only the necessary number of high-probability differential diagnoses rather than exhaustively listing all possible conditions. This selective generation approach maintains diagnostic accuracy while reducing the computational and presentational complexity of the output.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentUS20250336527A1High probability differential diagnoses generator and smart electronic medical record
Publication Date: 2025.10.30 KABIR AZAD ALAMGIR
  • US20250336527A1 patent drawing
  • US20250336527A1 patent drawing
  • US20250336527A1 patent drawing

AI summary

A method of diagnosing medical conditions using artificial technology, which combines elements of Ockham's Razor and modified utilization of likelihood Ratio/Bayesian Theorem. The system employs standardized smart weight to assess presenting symptoms, assigning scores to each diagnosis related sign and symptom, and setting a generalized cut-off point to confirm diagnoses and link them with evidence-based treatments based on severity of illness scores calculated by the system, as well as simplified smart weight algorithms to achieve accurate results without relying on complex sensitivity and specificity data.