Probe Droplet Detection via Capacitance in Automatic Analyzers

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Solution Overview

Problem

Automatic analyzers face issues with liquid droplets adhering to probes, leading to inaccurate sample or reagent dispensing, as these droplets can contaminate containers and affect analysis results by altering the concentration of samples or reagents.

Innovation Solution

An automatic analyzer equipped with a detector, such as an electrode measuring capacitance, to detect liquid droplets on the probe surfaces, and a controller to manage the cleaning process, ensuring accurate dispensing by identifying and removing adhering droplets.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the probe is used for sucking and discharging fluid multiple times, then productivity increases, but liquid droplets adhere to the outer surface of the probe causing contamination and analysis errors

Engineering Contradiction:
Improvenumber of sucking and discharging operationsVSAvoidaccuracy of analysis
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The detector measures capacitance before each sucking operation to detect liquid droplets in advance. If droplets are detected, the cleaning mechanism activates to clean the probe surface before the next operation, preventing contamination of samples or reagents and ensuring analysis accuracy is maintained throughout extended use

Inventive Principle:
Principle #10Preliminary action

2Productivity

If the probe outer surface deteriorates or becomes dirty, then liquid droplets form more easily, but continued use maintains productivity

Engineering Contradiction:
Improvecontinuous operation capabilityVSAvoidliquid droplet formation
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The detector provides continuous feedback by measuring capacitance between the probe and surrounding components. When capacitance changes indicate liquid droplet presence on the probe surface, the system automatically triggers the cleaning mechanism to remove droplets, preventing the cumulative effect of surface deterioration and maintaining low droplet formation throughout continuous operation

Inventive Principle:
Principle #23Feedback

3Reliability

If cleaning fluid adheres to the probe outer surface, then the probe appears clean, but subsequent sampling is contaminated by the cleaning fluid

Engineering Contradiction:
Improvecleanliness of probeVSAvoidconcentration accuracy of sample
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The detector measures capacitance after cleaning operations to verify that cleaning fluid has evaporated or been removed from the probe surface before the next sampling operation. This preliminary check prevents contaminated samples from being taken, ensuring both probe cleanliness and sample concentration accuracy are maintained

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively prevents liquid droplets from contaminating containers, maintaining the concentration integrity of samples and reagents, thereby enhancing the accuracy and reliability of analysis results.

Implementation Method 1

a detector (50) configured to detect that the probe (40) is in contact with a liquid

Methodology Applied
Scientific EffectCapacitance: Capacitance

Data Source

PatentUS20240264190A1Automatic analyzer and method for detecting adhesion of liquid droplet to probe
Publication Date: 2024.08.08 CANON KK
  • US20240264190A1 patent drawing
  • US20240264190A1 patent drawing
  • US20240264190A1 patent drawing

AI summary

An automatic analyzer includes a probe, a detector, and a controller. The probe sucks and discharges a sample and/or a reagent. The detector detects that the probe is in contact with a liquid. The controller detects that a liquid droplet adheres to the probe based on a detection result of the detector.