Probiotic Composition for Low Aerobic Capacity
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Solution Overview
Problem
Current studies on probiotics primarily focus on improving exercise performance in individuals with general aerobic exercise capacity, neglecting the impact of innate factors on exercise performance, particularly for those with low intrinsic aerobic exercise capacity, which affects physiological composition and disease susceptibility.
Innovation Solution
A complex probiotic composition comprising Lactobacillus rhamnosus GKLC1, Bifidobacterium lactis GKK24, and Clostridium butyricum GKB7 is administered orally for an extended period to improve exercise performance in subjects with low intrinsic aerobic exercise capacity, reducing serum lactic acid and urea nitrogen, and increasing liver and muscle glycogen content.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If probiotics are used to improve exercise performance in the general population, then exercise endurance and recovery are improved, but the specific benefits for individuals with low intrinsic aerobic exercise capacity are not achieved
Solution Approach 1:
The patent applies local quality by selecting specific probiotic strains (Lactobacillus rhamnosus GKLC1, Bifidobacterium lactis GKK24, Clostridium butyricum GKB7) that are particularly effective for individuals with low intrinsic aerobic exercise capacity. The composition is tailored to address the specific physiological needs of this subgroup, including their higher susceptibility to metabolic diseases and lower exercise endurance, rather than using a generic probiotic formulation for the entire population.
Solution Approach 2:
The patent implements preliminary action by administering the probiotic composition before exercise performance degradation occurs. The probiotics are given continuously for at least 28 days to pre-establish beneficial physiological changes, such as improving mitochondrial function and reducing inflammation, which then enhance exercise performance and prevent metabolic complications before they arise.
2Productivity
If acquired efforts such as training and diet control are used to improve exercise performance, then overall performance is improved, but innate constitutional differences remain
Solution Approach 1:
The patent applies parameter changes by modifying the physiological parameters of individuals with low intrinsic exercise capacity through probiotic administration. The probiotics alter key physiological parameters including mitochondrial density, oxidative enzyme activity, and inflammatory markers, thereby changing the body's intrinsic capabilities to improve exercise performance and reduce the impact of constitutional variability.
Solution Approach 2:
The patent uses probiotics as an intermediary substance that mediates between innate constitutional differences and acquired exercise performance. The probiotics act as a biological modulator that can compensate for low intrinsic exercise capacity by improving metabolic efficiency, reducing muscle fatigue, and enhancing recovery, thereby bridging the gap between genetic limitations and training achievements.
3Duration of action of stationary object
If probiotics are administered to reduce serum lactic acid and urea nitrogen, then exercise recovery is improved, but the mechanism for increasing glycogen storage is not fully explained
Solution Approach 1:
The patent applies continuity of useful action by administering the probiotic composition continuously for at least 28 days to maintain and enhance glycogen storage capabilities. The prolonged administration ensures that the probiotics continuously support liver and muscle glycogen synthesis, preventing depletion during exercise and maintaining energy reserves throughout the recovery period, thereby extending the beneficial effects on both recovery and energy storage.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The probiotic composition effectively enhances exercise performance by reducing serum lactic acid and urea nitrogen, decreasing offal fat proportion, and increasing glycogen storage in the liver and muscle, thereby improving overall physiological state and disease prevention.
Implementation Method 1
Probiotics are generally defined as bacteria that are beneficial to human health and can multiply in the human intestinal tract and are not pathogenic. Usually, the probiotics can regulate physique and change some metabolic pathways of the human body and achieve functions such as improving the overall gastrointestinal tract and metabolic capacity.
Data Source
AI summary
The present disclosure relates to a complex probiotic composition and a method for improving exercise performance of a subject with low intrinsic aerobic exercise capacity. The complex probiotic composition, which includes Lactobacillus rhamnosus GKLC1, Bifidobacterium lactis GKK24 and Clostridium butyricum GKB7, administered to the subject with the low intrinsic aerobic exercise capacity in a continuation period, can effectively reduce serum lactic acid and serum urea nitrogen after aerobic exercise, reduce proportion of offal fat and/or increase liver and muscle glycogen contents, thereby being as an effective ingredient for preparation of various compositions.