Probiotic Composition Reducing Feces Toxins

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Solution Overview

Problem

Current treatments for Irritable Bowel Syndrome (IBS) and diarrhea, particularly those caused by feces toxins, lack effective solutions, as existing methods only alleviate symptoms without addressing the root cause of feces toxin levels.

Innovation Solution

Administering a composition containing live beneficial bacteria such as Bacillus, Clostridium, and Bifidobacterium, along with prebiotics, to reduce feces toxin levels and treat IBS and diarrhea, with the bacteria forming a protective layer in the intestinal walls, inhibiting harmful bacteria, and promoting digestion.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional means (liquid, nutrients, medication) are administered to alleviate diarrhea symptoms, then symptom relief is achieved, but the root cause (feces toxin levels) is not addressed

Engineering Contradiction:
Improvesymptom relief effectivenessVSAvoidfeces toxin levels
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent utilizes beneficial bacteria (probiotics) that colonize the intestine and convert the harmful environment caused by feces toxins into a beneficial one. These bacteria produce substances that neutralize toxins, compete with harmful bacteria for resources, and restore intestinal balance, thereby converting the harmful toxin-rich environment into a beneficial therapeutic condition.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent introduces beneficial bacteria as intermediary organisms that mediate between the host and the harmful toxins. These bacteria act as a biological barrier and active agent that directly interacts with feces toxins, breaking them down or neutralizing them, thereby protecting the host from direct toxin damage while addressing the root cause.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-generated harmful factors

If live beneficial bacteria are administered to reduce feces toxin levels, then the root cause is addressed and symptom relief is achieved, but the treatment complexity increases compared to traditional means

Engineering Contradiction:
Improvefeces toxin levelsVSAvoidtreatment composition complexity
Core Design Contradiction:
Object-generated harmful factorsVSDevice complexity

Solution Approach 1:

The patent employs live beneficial bacteria that possess self-replicating and self-regulating capabilities. Once administered, these bacteria colonize the intestine autonomously, continuously producing beneficial substances and neutralizing toxins without requiring external intervention. This self-service mechanism simplifies the overall treatment system despite the biological complexity of the bacteria themselves.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent changes the fundamental parameter of intestinal microecology by introducing live bacteria that alter the chemical and biological parameters of the gut environment. This includes changing pH levels, producing antimicrobial substances, and modifying toxin concentrations, thereby addressing the root cause through parameter transformation rather than direct toxin removal.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If multiple types of beneficial bacteria are combined in the composition, then the efficacy in reducing feces toxins is enhanced, but the manufacturing complexity increases

Engineering Contradiction:
Improvefeces toxin reduction efficacyVSAvoidcomposition production difficulty
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent combines multiple strains of beneficial bacteria (such as Lactobacillus, Bifidobacterium, and Saccharomyces) into a single composition that works synergistically. Each strain targets different aspects of toxin reduction and intestinal health, and their combined effect is greater than the sum of individual effects, thereby enhancing efficacy while managing manufacturing complexity through standardized formulation.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates a composite probiotic composition that integrates multiple bacterial strains with complementary functions. This composite approach allows each strain to contribute its unique metabolic capabilities to toxin reduction, while the overall formulation is designed to maintain stability and ease of production through standardized manufacturing processes for multi-strain preparations.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Significantly reduces feces toxin levels, alleviates symptoms of IBS and diarrhea, including abdominal pain and constipation, with high efficacy rates and no reported side effects, as demonstrated in various clinical examples.

Implementation Method 1

these bacteria are effective in treating IBS and diarrhea... the bacteria forming a protective layer in the intestinal walls, inhibiting harmful bacteria

Methodology Applied
Scientific EffectProtective layer formation:

Implementation Method 2

live bacteria, such as Bacillus, Clostridium, and Bifidobacterium, reduce the feces toxin levels

Methodology Applied
Scientific EffectBiological degradation: Decomposition (biological)

Data Source

PatentUS7785581B2Composition and method for reducing feces toxins and treating digestive disorders
Publication Date: 2010.08.31 QINGDAO EASTSEA PHARMA

AI summary

This invention relates to a method of lowering feces toxin levels and treating digestive disorders (e.g., Irritable Bowel Syndrome or diarrhea) with a composition containing a live beneficial bacterium, a prebiotic, or both. This method includes first identifying a subject in need thereof and then administering to the subject an effective amount of the composition. Also within the scope of this invention is a composition including both a live beneficial bacterium and a prebiotic.