Probiotic Composition with Prebiotics and Lactoferrin for Gut Survival
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing probiotic compositions face challenges in surviving manufacturing processing and transit through the gastrointestinal tract, leading to reduced efficacy in maintaining intestinal health and combating dysbioses caused by stress, antibiotics, and dietary imbalances.
Innovation Solution
A probiotic composition comprising Bifidobacterium longum, Lactobacillus helveticus, and Lactobacillus plantarum, combined with prebiotics like inulin and fructose, mineral salts, lactoferrin, and optionally glutathione, to enhance survival and colonization in the gut, promoting intestinal health and immune modulation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If probiotics are administered in traditional formulations, then they can be delivered to consumers, but their survival through manufacturing processing and gastrointestinal transit is insufficient
Solution Approach 1:
The patent employs prebiotic materials (inulin, fructooligosaccharides, galactooligosaccharides) as intermediary substances that protect probiotic bacteria during gastrointestinal transit. These prebiotics form a protective matrix around the probiotics, shielding them from harsh gastric conditions while providing nourishment for their survival and subsequent colonization of the gut microbiota.
Solution Approach 2:
The invention creates composite probiotic formulations combining multiple probiotic strains (Lactobacillus species, Bifidobacterium species, Streptococcus thermophilus) with prebiotic materials and functional ingredients (lactoferrin, mineral salts, antioxidants). This composite approach enhances overall survival rates by leveraging synergistic effects among different components, where each element contributes to protecting and sustaining the probiotics through manufacturing and digestive processes.
2Reliability
If probiotic compositions are enhanced with multiple protective components, then survival and colonization efficacy is improved, but formulation complexity increases
Solution Approach 1:
The patent integrates multiple functional ingredients that serve several purposes simultaneously. For example, prebiotic materials not only protect probiotics during transit but also serve as food sources for probiotic colonization in the gut. Lactoferrin provides both antimicrobial protection against pathogens and immunomodulatory benefits. Mineral salts contribute to both structural stability of the formulation and physiological functions in the host. This multi-functionality reduces the need for separate protective mechanisms, thereby managing complexity while enhancing efficacy.
Solution Approach 2:
The invention merges traditionally separate functional components into a unified probiotic formulation. Probiotics, prebiotics, lactoferrin, mineral salts, and antioxidants are combined into a single integrated product that delivers multiple benefits simultaneously. This consolidation simplifies the overall intervention strategy compared to administering multiple separate supplements, while achieving enhanced survival and colonization effects through the synergistic interaction of all components.
Data Source
AI summary
The present invention relates to compositions comprising probiotic and prebiotic components, mineral salts, lactoferrin, and possibly saccharomycetes, which perform correct, effective colonisation of the probiotic components administered, with enteric consequences which involve maintaining and/or restoring intestinal health and preventing the consequences of common dysbioses of the digestive tract caused by stress, incorrect dietary habits and antibiotic treatments. Said compositions also have a concomitant anti-inflammatory and immunomodulating action.