Probiotic Microbial Composition for Poultry Pathogen Exclusion
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Solution Overview
Problem
The poultry industry faces challenges in increasing production efficiency while maintaining animal health and reducing environmental impact, as large-scale farming leads to microbial pathogen issues and resource inefficiencies, making it difficult to meet growing global demand for poultry products sustainably.
Innovation Solution
Administering a microbial composition comprising purified bacteria and fungi with specific 16S and ITS nucleic acid sequences to improve desirable traits in fowl, such as immune response, growth rate, and pathogen exclusion, formulated into various carriers for effective administration.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If poultry population density is increased to meet global demand, then production efficiency improves, but microbial pathogen incidence increases
Solution Approach 1:
The patent applies preliminary anti-action by administering probiotic microbial compositions to poultry before pathogen exposure occurs. The beneficial microbes establish colonization in the gut microbiome, creating resistance to subsequent pathogen invasion. This preventive approach allows high-density farming while maintaining health by pre-establishing protective microbial populations that compete with and inhibit pathogens.
Solution Approach 2:
The patent uses probiotic microorganisms as intermediaries between the poultry host and potential pathogens. These beneficial microbes act as a biological barrier, occupying ecological niches and resources that would otherwise be available to harmful pathogens. The intermediary microbes modulate the immune system and create a protected environment that enables high-density farming without proportional increases in disease incidence.
2Object-affected harmful factors
If conventional antibiotics are used to control pathogens, then pathogen incidence decreases, but harmful residual effects increase
Solution Approach 1:
The patent converts the potential harm of microbial competition into a benefit by using beneficial probiotic microorganisms that naturally compete with pathogens for resources and space. Instead of using antibiotics that kill both beneficial and harmful microbes, the patent employs harmless beneficial microbes that outcompete pathogens through production of bacteriocins, organic acids, and other antimicrobial substances. This transforms a potentially harmful chemical intervention into a beneficial biological process that reduces pathogens without leaving harmful residuals or promoting resistance.
3Productivity
If scale-up of current high-input systems is implemented, then poultry yield increases, but environmental impact worsens
Solution Approach 1:
The patent applies self-service by using probiotic microorganisms that naturally perform functions beneficial to both poultry health and environmental sustainability. The probiotics enhance feed conversion efficiency, reducing waste production. They also modulate the gut microbiome to improve nutrient absorption and reduce excretion of harmful substances. This self-service approach allows increased poultry yield without proportional increases in environmental waste, as the microbial system automatically optimizes resource utilization and waste reduction.
Data Source
AI summary
The disclosure relates to isolated microorganisms-including novel strains of the microorganisms-microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.