Probiotic Oral Composition for Long-Lasting Bad Breath Control
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Solution Overview
Problem
Current methods for managing bad breath, such as oral antiseptics, are chemically harmful and provide only temporary relief, lacking a safe and effective long-term solution for ameliorating oral diseases like bad breath, caries, and periodontal disease.
Innovation Solution
A pharmaceutical or food composition containing a strain combination of Lactobacillus gasseri HHuMIN D and Lacticaseibacillus paracasei OK, which inhibits oral disease-causing bacteria and reduces bad breath by using live or dead cells and their culture solutions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If oral antiseptics are used to manage bad breath, then volatile sulfur compounds are chemically removed providing temporary relief, but oral tissue damage risk increases with long-term use
Solution Approach 1:
The patent utilizes the natural antibacterial properties of lactic acid bacteria (Lactobacillus gasseri and Lacticaseibacillus paracasei) to convert the harmful effect of oral pathogens into a beneficial outcome. These probiotic strains selectively inhibit bad breath-causing bacteria while producing beneficial metabolites, thereby managing bad breath through biological mechanisms rather than chemical antiseptics, eliminating tissue damage risk while maintaining effectiveness
Solution Approach 2:
The patent changes the fundamental parameter of bad breath management from chemical removal of volatile sulfur compounds to biological inhibition of pathogen growth. By introducing live or dead lactic acid bacteria cells that produce bacteriocins and organic acids, the system shifts from symptomatic chemical treatment to preventive biological control, maintaining pH balance and oral microbiome equilibrium while eliminating the need for harsh antiseptics
2Reliability
If chemical compounds are used to remove volatile sulfur compounds, then bad breath is temporarily reduced, but long-term solution is lacking due to safety concerns
Solution Approach 1:
The patent establishes continuous beneficial action through the establishment of a balanced oral microbiome. Live lactic acid bacteria cells continuously produce antibacterial substances and maintain acidic pH levels that prevent pathogen recolonization. The probiotic formulation ensures sustained inhibition of volatile sulfur compound production through continuous bacterial metabolism, providing long-term protection rather than temporary chemical masking
Solution Approach 2:
The lactic acid bacteria exhibit self-service properties by autonomously producing bacteriocins, hydrogen peroxide, and organic acids that continuously inhibit pathogenic bacteria. The probiotic strains self-regulate the oral environment by maintaining pH balance and competing for nutrients and attachment sites, creating a self-sustaining protective system that does not require repeated chemical applications
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The strain combination effectively inhibits the growth and attachment of harmful oral bacteria, significantly reducing volatile sulfur compounds and improving oral health indicators, as confirmed by human tests.
Implementation Method 1
the present inventors found a strain combination having excellent selective antibacterial activity while having low risk of human and environmental toxicity
Implementation Method 2
An oral antiseptic chemically removes volatile sulfur compounds (VSC), which are the cause of bad breath
Data Source
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AI summary
Disclosed is a composition for ameliorating, preventing or treating an oral disease containing a strain combination of Lactobacillus gasseri HHuMIN D and Lacticaseibacillus paracasei OK. The strain combination is capable of inhibiting oral harmful bacteria, thus being highly effective in ameliorating, preventing, and treating oral diseases including bad breath, tooth decay, and periodontal disease.