Probiotic Sanitizer Composition for Pathogen Detachment

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Solution Overview

Problem

Traditional skin cleaning and disinfection methods are ineffective in removing pathogens that adhere strongly to the skin, leading to increased infection risk and transmission, and there is a need for alternative antimicrobial-free solutions to maintain skin microbiome balance.

Innovation Solution

A topical composition containing 0.02 wt.% to 10.0 wt.% of probiotics, probiotic derivatives, or prebiotics, combined with 40.0 wt.% to 95 wt.% C1-6 alcohols and optional humectants, emollients, and viscosity modifiers, designed to reduce pathogen binding and restore skin's natural bacterial balance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If traditional soap or waterless sanitizer is used to clean skin, then general cleaning is achieved, but pathogens that adhere strongly to skin remain and are difficult to remove or kill

Engineering Contradiction:
Improvepathogen removal effectivenessVSAvoidinfection prevention reliability
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent introduces probiotics as intermediary organisms that compete with pathogens for binding sites on skin. These beneficial microbes act as mediators by occupying adhesion sites, thereby preventing pathogen attachment without directly killing the pathogens. This competitive exclusion mechanism allows removal of adherent pathogens while maintaining skin microbiome balance.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention changes the microbial parameter of the skin surface by introducing specific probiotic strains that alter the ecological balance. By changing the composition and behavior of resident microbes, the system achieves enhanced pathogen removal capability while maintaining skin health and preventing infection.

Inventive Principle:
Principle #35Parameter changes

2Object-affected harmful factors

If more antimicrobials are used to control pathogens, then pathogen levels decrease, but skin microbiome balance is disrupted and harmful effects increase

Engineering Contradiction:
Improvepathogen controlVSAvoidmicrobiome disruption and side effects
Core Design Contradiction:
Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The patent converts the harmful presence of pathogens into a beneficial outcome by using probiotics to outcompete them for resources and binding sites. Instead of directly attacking pathogens with antimicrobials, the system uses beneficial microbes to displace harmful ones, thereby controlling pathogen levels while avoiding microbiome disruption and associated harmful effects.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

3Stability of the object's composition

If probiotics are used to control microbes on skin, then skin microbiome balance is restored, but the ability to directly kill pathogens is reduced compared to traditional antimicrobials

Engineering Contradiction:
Improveskin microbiome balanceVSAvoidpathogen killing efficiency
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The patent applies probiotics in advance to occupy binding sites and establish a protective microbial barrier before pathogens can adhere. This preliminary action prevents pathogen attachment and colonization, achieving effective pathogen control through prevention rather than direct killing, thereby maintaining both microbiome balance and pathogen reduction.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS11998575B2Sanitizer composition with probiotic/prebiotic active ingredient
Publication Date: 2024.06.04 GOJO IND INC
  • US11998575B2 patent drawing
  • US11998575B2 patent drawing
  • US11998575B2 patent drawing

AI summary

A topical sanitizing composition for restoring skin's natural balance of bacteria is provided. The topical sanitizing composition includes about 0.02 wt. % to 10.0 wt. % of an active ingredient, at least about 40 wt. % of one or more C1-6 alcohols; and water. The active ingredient comprises one or more of a probiotic, probiotic derivative, and a prebiotic.