Probiotic and Vitamin B Complex Composition for Lipid Reduction

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Solution Overview

Problem

Current obesity and lipid-related metabolic disease treatments are ineffective in reducing blood lipid and cholesterol levels, often causing adverse effects and have low persistence of efficacy, while natural substances used for weight control are costly and have low effective concentrations.

Innovation Solution

A combination of probiotics and a vitamin B complex is used to promote vitamin B absorption, synergistically reducing blood lipid levels by inhibiting cholesterol absorption and improving metabolic balance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If artificially synthesized obesity therapeutic drugs are used, then weight control effect is achieved, but adverse effects occur and persistence of efficacy is low

Engineering Contradiction:
Improvepersistence of efficacyVSAvoidadverse effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical composition parameters by using naturally occurring probiotics and vitamin B complex instead of synthetic drugs, thereby maintaining therapeutic efficacy while reducing adverse effects and improving persistence of action

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent combines probiotics and vitamin B complex in a composite formulation, where the synergistic interaction between these components enhances the persistence of efficacy while minimizing harmful side effects associated with single-agent synthetic therapies

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If natural substances are used for weight control, then adverse effects are minimized, but effective concentration is low and costs are high

Engineering Contradiction:
Improveadverse effectsVSAvoideffective concentration
Core Design Contradiction:
Object-affected harmful factorsVSQuantity of substance

Solution Approach 1:

The patent merges probiotics and vitamin B complex into a single composition, where the combination enhances the effective concentration of active components while maintaining the safety profile of natural substances, thereby resolving the contradiction between low effective concentration and high safety

Inventive Principle:
Principle #5Merging (Combining)

3Reliability

If current obesity treatments are used, then body weight reduction is attempted, but blood lipid and cholesterol levels are not effectively reduced

Engineering Contradiction:
Improveeffectiveness in reducing blood lipid levelsVSAvoidmetabolic improvement efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent introduces probiotics as intermediary agents that mediate the metabolic process, enhancing the body's natural ability to reduce blood lipid and cholesterol levels, thereby improving both reliability and productivity of the treatment

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentEP3318251B1Composition for preventing or treating obesity or lipid-related metabolic disease
Publication Date: 2021.03.24 CELL BIOTECH CO LTD
  • EP3318251B1 patent drawingFigure 1~2
  • EP3318251B1 patent drawingFigure 3~4
  • EP3318251B1 patent drawingFigure 5~6

AI summary

The present invention provides a pharmaceutical composition and a food composition for preventing or treating lipid-related metabolic disease, which contain, as active ingredients, probiotics and a vitamin B complex. When the composition comprising the probiotics and the vitamin B complex is used, it may further promote in vivo absorption of the vitamin B complex, and may induce a synergistic effect on a reduction in blood lipid levels, thereby exhibiting an effect on the alleviation, prevention or treatment of obesity and lipid-related metabolic disease.