Programmable TTFields Electrode Arrays for Multi-Tumor Treatment

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Solution Overview

Problem

Existing TTF systems lack dynamic reassignment of array elements, current monitoring, and effective management of heat and peripheral nerve stimulation, leading to reduced effectiveness and patient discomfort.

Innovation Solution

A modular system with independently programmable electrode elements, dynamic control of firing sequences, and heat management through strategic array placement and cooling mechanisms, along with a magnetic tool for real-time adjustments and a flexible application process.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If multiple separate TTFields devices are used to treat multiple tumors, then each tumor can receive appropriate treatment, but the device complexity and number of components increase significantly

Engineering Contradiction:
Improveability to treat multiple tumorsVSAvoidnumber of electrode elements
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system divides the treatment function into independently controllable electrode elements (master and slave electrodes) that can be selectively activated. Each electrode element can be independently programmed with specific frequencies and firing configurations, allowing targeted treatment of multiple tumors using a single integrated device rather than multiple separate devices.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The TTFields device is designed with universal functionality to treat multiple tumors simultaneously or sequentially. The control device can dynamically program frequency ranges and firing sequences for multiple electrode elements, enabling one device to perform the function of multiple separate devices through software-controlled configuration.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Adaptability or versatility

If multiple separate TTFields devices are used for multiple tumors, then each tumor receives dedicated treatment, but the treatment cost increases

Engineering Contradiction:
Improvemulti-tumor treatment capabilityVSAvoidnumber of devices required
Core Design Contradiction:
Adaptability or versatilityVSQuantity of substance

Solution Approach 1:

The patent merges multiple treatment functions into a single TTFields device. By combining multiple master and slave electrode elements in one device with a unified control system, the invention eliminates the need for multiple separate devices, thereby reducing the quantity of equipment required and associated costs while maintaining the ability to treat multiple tumors.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The device achieves multi-tumor treatment capability through universal programming of electrode elements. The control device can configure different frequency ranges and firing sequences for different electrode pairs, allowing one device to replace multiple specialized devices through software-defined treatment protocols.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Adaptability or versatility

If multiple separate TTFields devices are used, then comprehensive tumor coverage is achieved, but the programming and operational complexity increases

Engineering Contradiction:
Improvetreatment coverageVSAvoidprogramming complexity
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

The control device automatically manages the complexity of programming multiple electrode elements. The system can dynamically program frequency ranges and firing sequences without requiring manual configuration of each electrode, reducing operational complexity. The device serves itself by internally coordinating the multiple electrode elements under unified control.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The control device acts as an intermediary between the operator and the multiple electrode elements. It abstracts the complexity of programming by providing a unified interface that manages frequency ranges, firing configurations, and sequences for all electrode elements, shielding the user from the underlying complexity while maintaining comprehensive treatment coverage.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enhances treatment efficacy by maintaining optimal field strength, reducing heat, and minimizing patient discomfort, while ensuring safety and compliance.

Implementation Method 1

a field generator (102) to generate electrical signals in the frequency range, the electrical signals being directed to at least two of the plurality of electrode elements

Methodology Applied
Scientific EffectElectromagnetic field generation: Electromagnetic Induction

Data Source

PatentEP4434573B1Apparatus for treating multiple tumors in patients with metastatic disease by electric fields
Publication Date: 2026.05.13 LIFEBRIDGE INNOVATIONS PBC
  • EP4434573B1 patent drawingFigure 1
  • EP4434573B1 patent drawingFigure 2A~2B
  • EP4434573B1 patent drawingFigure 3A~3D

AI summary

An electronic device for delivering a plurality of tumor treating electromagnetic fields to a patient including a plurality of electrode elements each being independently programmable, a control device and a field generator. The control device is configured to dynamically program a frequency range, a firing configuration and a firing sequence for the plurality of electrode elements. The field generator generates electrical signals in the frequency range, the electrical signals being directed to at least two of the plurality of electrode elements. The plurality of electrode elements including both master and slave electrode elements.