Propolis and Ginkgo Leaf Extract Composition for Cognitive Function
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Solution Overview
Problem
Current treatments for dementia, particularly Alzheimer's type, are only temporary and do not address the fundamental issue of amyloid β accumulation, with no established method for prevention or reversal of cognitive decline.
Innovation Solution
A composition containing propolis and ginkgo leaf extract, optionally combined with other ingredients like phosphatidylserine, coffee fruit extract, gotu kola extract, and curcumin, which acts as an antioxidant, antisaccharification, neurite outgrowth promoter, and cognitive function improver, potentially addressing amyloid β production and inflammation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional therapeutic drugs are used for dementia treatment, then the progress of dementia is temporarily delayed, but no fundamental treatment effect is achieved and amyloid β accumulation remains
Solution Approach 1:
The patent combines multiple natural ingredients (ginkgo leaf extract, propolis, phosphatidylserine, curcumin, gotu kola extract, coffee fruit extract, DHA, EPA) into a composite formulation that works synergistically to address amyloid β accumulation, oxidative stress, and inflammation simultaneously, providing both temporary relief and fundamental treatment effects that single drugs cannot achieve
Solution Approach 2:
The invention uses a composite formulation combining extracts from multiple plant sources with specific biochemical compounds (phosphatidylserine, curcumin, gotu kola extract, coffee fruit extract, DHA, EPA) to create a multi-functional treatment that addresses multiple pathways of dementia pathology including amyloid β production, oxidative stress, and neuroinflammation
2Reliability
If no preventive method is established, then cognitive function decline cannot be prevented in early stages, but current treatments only address advanced dementia
Solution Approach 1:
The patent enables preliminary preventive action by providing a formulation that can be administered in early stages of cognitive decline or even before symptoms appear. The combination of antioxidants, anti-inflammatory agents, and neuroprotective compounds prevents amyloid β accumulation and cognitive decline before they become irreversible, allowing intervention at the reversible phase
3Ease of manufacture
If single ingredient treatments are used, then specific cognitive functions may be supported, but synergistic effects for comprehensive brain protection are not achieved
Solution Approach 1:
The patent merges multiple natural ingredients with complementary mechanisms of action into a single formulation: ginkgo leaf extract for blood flow and antioxidant support, propolis for anti-inflammatory and antioxidant effects, phosphatidylserine for membrane integrity, curcumin for amyloid β inhibition, gotu kola extract for neuroprotection, coffee fruit extract for antioxidant activity, and omega-3 fatty acids for neuronal health. This combination achieves synergistic effects for comprehensive brain protection
Data Source
AI summary
There are disclosed an antioxidant agent, an antisaccharification agent, a neurite outgrowth promoting agent, and a cognitive function improving agent, which contain propolis and a ginkgo leaf extract as active ingredients.