Prostatic Urethral Expander Structure to Reduce Migration and Encrustation
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Solution Overview
Problem
Existing prostatic stents for treating benign prostatic hyperplasia (BPH) suffer from high rates of migration, encrustation, blockage, and pain due to their circumferential design and rigidity, which do not accommodate the unique anatomy of the prostatic urethra, leading to complications such as incontinence and difficulty in removal.
Innovation Solution
A resiliently deformable undulating ring expander with longitudinal struts and prongs that conform to the prostatic urethra's anatomy, minimizing contact area and allowing for differential flexing, reducing encrustation and migration, and facilitating easy removal.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If traditional cylindrical stents are used to treat BPH, then the prostatic urethra can be supported to relieve symptoms, but the stents migrate to the bladder or membranous urethra causing incontinence and pain
Solution Approach 1:
The expander is divided into multiple segments including a proximal expansion element, a distal expansion element, and intermediate sections with transverse ridges. These segmented structures provide localized support at critical anatomical positions (bladder neck, verumontanum, external sphincter) while preventing migration to adjacent regions, thus resolving the contradiction between providing adequate support and preventing migration.
Solution Approach 2:
The expander features localized structural variations including transverse ridges at specific positions, varying wall thicknesses, and strategically placed expansion elements. These local quality modifications provide enhanced support where needed (e.g., at the bladder neck and verumontanum) while maintaining flexibility in other areas, preventing migration without requiring a completely rigid structure.
2Reliability
If rigid stents are used to maintain urethral patency, then immediate symptom relief is achieved, but the stents cause pain and do not accommodate natural urethral movements during urination and ejaculation
Solution Approach 1:
The expander transitions from a static rigid structure to a dynamic adaptable structure that can change its mechanical properties in response to physiological conditions. The intermediate sections with transverse ridges allow controlled flexibility and movement during urination and ejaculation, while the expansion elements maintain patency, thus resolving the contradiction between maintaining patency and accommodating natural movements.
Solution Approach 2:
The expander incorporates thin-walled sections and flexible intermediate portions that can deform and move with the natural physiological movements of the urethra during urination and ejaculation. These flexible regions reduce pain and discomfort while the expanded portions maintain adequate patency, resolving the contradiction between rigidity for patency and flexibility for comfort.
3Reliability
If circumferential ring stents are used to support the prostatic urethra, then the urethra is held open to improve urine flow, but the rings encrust and block the urethra
Solution Approach 1:
The expander is segmented into multiple sections with transverse ridges and spaced expansion elements rather than a continuous circumferential ring. This segmentation reduces the continuous surface area exposed to urine, minimizing encrustation sites while maintaining adequate urethral dilation through distributed support points, thus resolving the contradiction between maintaining patency and preventing encrustation.
Solution Approach 2:
The expander introduces longitudinal dimensionality with its elongated structure featuring transverse ridges and spaced expansion elements along its length, rather than relying solely on circumferential rings. This dimensional change creates a more three-dimensional support structure that maintains patency while reducing the continuous circumferential surface area that promotes encrustation.
4Reliability
If traditional stents are used to treat BPH, then immediate symptom relief is provided, but removal is difficult due to embedding in the urethral wall
Solution Approach 1:
The expander is designed with predetermined features that facilitate future removal, including a delivery catheter system that can be used for both insertion and extraction. The expansion elements and transverse ridges are configured to provide adequate symptom relief during use, while the overall结构设计 allows for controlled compression and removal through the urethra using the same delivery system, resolving the contradiction between effective treatment and ease of removal.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The undulating ring expander effectively dilates the prostatic urethra, reducing encrustation and migration risks while maintaining anatomical conformity, ensuring smooth urine flow and ease of removal without obstructing ejaculatory ducts or the verumontanum.
Implementation Method 1
The expander is resiliently deformable in a radial direction between a contracted orientation suitable for transluminal delivery to the target site through the body lumen and an expanded (deployed) orientation configured to effect in-situ dilation of the body lumen at the target site
Data Source
AI summary
A delivery device for positioning an implantable expander to a target location in a prostatic urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.


