Composite Prosthesis with Absorbable Coating for Adhesion Prevention
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Solution Overview
Problem
Existing textile reinforcement prostheses used in extraperitoneal surgeries are prone to causing adhesions and infections due to their nonabsorbable nature, which can lead to severe fibrous connections and complications in fragile tissues, especially when aseptic conditions are difficult to maintain.
Innovation Solution
A composite prosthesis with a porous textile support coated with a hydrophilic absorbable material forms a film that envelops and penetrates the microporous texture, reducing bacterial adhesion and promoting tissue integration without forming a plane layer, thereby minimizing adhesions and infections during the initial cicatrization phase.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Duration of action of stationary object
If a nonabsorbable textile support is used for reinforcement, then long-term structural support is provided, but adhesions and fibrous connections form on fragile tissues during the initial inflammatory phase
Solution Approach 1:
The prosthesis is segmented into two distinct functional zones: a protected zone coated with absorbable material for fragile tissue contact, and an unprotected zone for firm anchoring. This segmentation allows each zone to perform its specific function optimally without compromising the other.
Solution Approach 2:
Different regions of the prosthesis are given different properties: the protected zone has a smooth absorbable coating to prevent adhesions on fragile tissues, while the unprotected zone remains porous and nonabsorbable for strong anchoring in robust tissues. This local differentiation resolves the contradiction between preventing adhesions and providing long-term support.
2Adaptability or versatility
If a porous textile support is used, then tissue integration is promoted, but bacterial adhesion increases the greater the developed surface area
Solution Approach 1:
The prosthesis surface is segmented into protected and unprotected zones. The protected zone with absorbable coating provides a smooth surface that reduces bacterial adhesion, while maintaining the overall porous structure for tissue integration in the unprotected zone.
Solution Approach 2:
The absorbable coating acts as an intermediary layer between the bacterial environment and the textile support. This intermediate layer prevents direct contact between bacteria and the porous structure, reducing adhesion while still allowing the prosthesis to integrate with tissues.
3Object-affected harmful factors
If a smooth coating is applied to prevent adhesions, then bacterial adhesion is reduced, but tissue integration is hindered
Solution Approach 1:
The prosthesis is divided into protected and unprotected zones, allowing the smooth coating to prevent adhesions where needed while leaving other areas porous for tissue integration. This resolves the contradiction by applying smoothness only where adhesion prevention is critical.
Solution Approach 2:
The smooth absorbable coating is applied locally to the protected zone that contacts fragile tissues, while the rest of the prosthesis maintains its porous structure for tissue integration. This local application of smoothness prevents adhesions without compromising overall tissue integration capabilities.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution effectively protects fragile tissues from adhesions and bacterial adhesion, facilitating the cicatrization process and reducing the risk of infections, while allowing for rapid tissue integration and restoration of the original tissue structure.
Implementation Method 1
a hydrophilic absorbable material coats the textile support, forming a film enveloping and penetrating into the arrangement of threads, occluding at least the microporous texture
Implementation Method 2
said textile support defining a microporous texture comprising the interstices located between at least two threads at the sites of contact of one thread with at least one other thread
Data Source
AI summary
The present invention relates to a composite prosthesis for reinforcement of a tissue structure, including a porous textile support which includes an arrangement of threads each composed of at least one filament of nonabsorbable polymer material, said textile support defining a microporous texture including the interstices located between at least two threads at the sites of contact of one thread with at least one other thread, wherein, in at least one protected zone of the textile support, a hydrophilic absorbable material coats the textile support, forming a film enveloping and penetrating into the arrangement of threads, occluding at least the microporous texture, but without forming a plane layer covering at least one face of the textile support.It also relates to a process for preparing such a composite reinforcement prosthesis.