Endoluminal Prosthesis Removable Channels Coronary Perfusion

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Solution Overview

Problem

Current endovascular approaches for aortic valve and ascending aorta repair do not adequately address the complex anatomy of the region, risking temporary blockage of coronary arteries and insufficient repair, leading to complications and high morbidity and mortality rates.

Innovation Solution

An endoluminal prosthesis system with a valve replacement and stent framework, featuring removable channels and fenestrations for maintaining perfusion of branch vessels, allowing for secure deployment and minimizing risk to coronary arteries during procedures.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If endovascular approach is used for aortic valve and ascending aorta repair, then morbidity and mortality rates are reduced compared to open procedure, but the complex anatomy risks temporary blockage of coronary arteries and insufficient repair

Engineering Contradiction:

Improveprocedural safetyVSAvoidtemporary blockage of coronary arteries

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The prosthesis is divided into multiple segments including a main body portion, a first branch portion for the first coronary artery, and a second branch portion for the second coronary artery. This segmentation allows each portion to be independently positioned and deployed, ensuring that coronary artery openings are maintained open during the procedure while reducing the risk of temporary blockage.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The prosthesis is designed with pre-formed branch portions and openings that are prepared before deployment. The first and second branch portions are configured to align with and maintain the patency of the first and second coronary arteries respectively during the endovascular procedure, preventing temporary blockage before it can occur.

Inventive Principle:

Principle #10Preliminary action

2Object-affected harmful factors

If endovascular approach is used for aortic valve and ascending aorta repair, then invasive trauma is reduced, but repair sufficiency for complex anatomy is compromised

Engineering Contradiction:

Improveinvasive traumaVSAvoidrepair sufficiency

Core Design Contradiction:

Object-affected harmful factorsVSReliability

Solution Approach 1:

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The prosthesis simultaneously performs multiple functions: it replaces the aortic valve, repairs the ascending aorta, and maintains patency of both coronary arteries through its integrated branch portions. This multi-functionality allows sufficient repair of the complex aortic anatomy through a single endovascular procedure.

Inventive Principle:

Principle #6Universality (Multi-functionality)

3Object-affected harmful factors

If removable channel is introduced to maintain coronary perfusion during deployment, then procedural risk is reduced, but device complexity increases

Engineering Contradiction:

Improveprocedural riskVSAvoiddevice structure

Core Design Contradiction:

Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The removable channel is nested within the delivery catheter during the deployment procedure. The channel can be selectively removed or retained based on procedural needs, allowing it to serve its protective function during coronary artery engagement while being compactly stored within the delivery system when not in use.

Inventive Principle:

Principle #7Nested doll (Nesting)

Solution Approach 2:

The removable channel is designed to be extractable from the prosthesis structure after serving its protective function during deployment. This allows the channel to be removed once the coronary arteries are secured, simplifying the final implanted structure while having provided necessary protection during the critical deployment phase.

Inventive Principle:

Principle #2Taking out (Extraction)

Data Source

PatentEP2777608B1Endoluminal prosthesis system

Publication Date: 2021.12.29 COOK MEDICAL TECHNOLOGIES LLC

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Figure 6A~6C

AI summary

An endoluminal prosthesis (10) comprises a graft (20) having a tubular body comprising proximal and distal ends (22,24), inner and outer surfaces, and partially and fully deployed states. A temporary channel (120) is disposed external to the outer surface of the graft (20) in the partially deployed state. The temporary channel (120) begins at one of the proximal and distal ends (22,24) of the graft (20), and extends along only a portion of a longitudinal length of the graft (20). The temporary channel (120) is removed when the graft (20) is in a fully deployed state.