Prosthetic Valve Tensioning for Precise Coaptation Alignment

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Solution Overview

Problem

Existing methods for tricuspid regurgitation (TR) require complex and invasive open-heart procedures, which are risky and painful, and there is a need for a simpler and easier solution for heart valve replacement.

Innovation Solution

A prosthetic implant delivery system with a tensioning mechanism that includes an outer sheath, a tensioning rod, and a control handle to deploy and position a prosthetic valve implant using adjustable control interfaces for precise alignment and orientation of the coaptation structure relative to the anchor member.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If open-heart procedures are used for valve replacement, then the valve can be replaced effectively, but the procedure becomes highly invasive with significant risks and painful recovery

Engineering Contradiction:
Improvevalve replacement effectivenessVSAvoidinvasiveness and surgical risks
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces the mechanical open-heart surgical system with a percutaneous delivery system that uses catheter-based delivery and balloon expansion to implant the valve through a minimally invasive approach, substituting traditional surgical mechanics with interventional radiology-style mechanics

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces a delivery catheter and balloon as intermediary devices that mediate between the operator and the valve implant, allowing the valve to be delivered and deployed through a peripheral vessel without direct surgical access to the heart

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If traditional valve delivery methods are used, then the procedure is simpler, but precise positioning and orientation of the coaptation structure cannot be achieved

Engineering Contradiction:
Improvedelivery procedure simplicityVSAvoidcoaptation structure positioning precision
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The patent employs a dynamic positioning system where the coaptation structure can be adjusted and repositioned during the procedure using a control mechanism that allows real-time modification of the structure's orientation and position relative to the anchor member

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent divides the valve structure into separable components including the anchor member and the coaptation structure connected by an adjustable connection mechanism, allowing independent positioning and orientation adjustment of each component for precise alignment

Inventive Principle:
Principle #1Segmentation

Data Source

PatentEP4216874B1Prosthetic implant, delivery system and delivery apparatus
Publication Date: 2025.11.12 SINGAPORE HEALTH SERVICES PTE LTD
  • EP4216874B1 patent drawingFigure 1A~1B
  • EP4216874B1 patent drawingFigure 2
  • EP4216874B1 patent drawingFigure 3A

AI summary

A prosthetic implant including an anchor member; at least one resilient tethering strut extending from the anchor member; a coaptation structure coupled to an end of the at least one resilient tethering strut; and a tensioning unit extending between the anchor member and the coaptation structure. The tensioning unit including a flexible hollow tubing, and a tensioning wire extending therethrough with a first end of the tensioning wire fixed at a junction between a first end of the flexible hollow tubing and the coaptation structure and with a second end of the tensioning wire extending out from a second end of the flexible hollow tubing. The second end of the tensioning wire being pullable away from the second end of the flexible hollow tubing to bend the flexible hollow tubing and the at least one resilient tethering strut to move the coaptation structure relative to the anchor member.