Prosthetic Valve Anterior Leaflet Deflection for Outflow Clearance
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Solution Overview
Problem
Traditional surgical and minimally invasive procedures for treating mitral regurgitation often result in obstructed blood flow, turbulence, and disruption of the natural hemodynamics due to prosthetic heart valves, leading to potential hemodynamic problems.
Innovation Solution
A prosthetic heart valve with a radially expandable anchor frame and leaflets that direct blood flow in a non-turbulent, circular manner along the posterior wall of the left ventricle, maintaining momentum and energy, and an anterior leaflet that deflects away from the left ventricular outflow tract during systole to ensure unobstructed outflow.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a traditional prosthetic heart valve is implanted, then the valve can close the mitral regurgitation, but it obstructs blood flow and causes turbulence
Solution Approach 1:
The prosthetic valve leaflets are designed with a circular configuration that directs blood flow in a circular pattern along the posterior wall of the left ventricle, following the natural curvature of the ventricular cavity. This curved flow path eliminates turbulence and maintains smooth, laminar flow throughout the ventricle, preventing the blood flow obstruction and turbulence caused by traditional straight-edged valve designs
2Reliability
If the prosthetic valve is designed to seal tightly, then regurgitation is prevented, but outflow tract obstruction occurs
Solution Approach 1:
The anterior prosthetic leaflet is designed with differentiated functionality: the majority of the leaflet spans the mitral valve annulus to provide effective sealing against regurgitation, while the distal portion is configured to deflect away from the left ventricular outflow tract during systole. This local differentiation allows the valve to maintain tight sealing where needed while preventing outflow obstruction where it would be harmful
Solution Approach 2:
The anterior leaflet is designed to be dynamic rather than static, automatically deflecting away from the left ventricular outflow tract during systole when blood is being ejected. This dynamic movement ensures that the leaflet provides effective sealing during diastole when closed, but clears the outflow tract during systole to prevent obstruction, adapting its position to the physiological cycle
Data Source
AI summary
A prosthetic mitral valve may be anchored in a native mitral valve. The prosthetic mitral valve preferably has a large anterior prosthetic leaflet that spans the entire width of the native anterior leaflet and the anterior prosthetic leaflet moves away from left ventricular outflow tract during systole to create a clear unobstructed outflow path.