Protease Cleaning Agent for Automatic Dosing on Dried-On Residues

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Solution Overview

Problem

Consumers face challenges with temperature-sensitive cleaning agents in automatic dishwashers, particularly when dealing with stubborn food residues like dried-on minced meat and egg yolk, and frequent rinsing is required due to prolonged loading times between wash cycles, leading to inefficiency and increased water usage.

Innovation Solution

A liquid cleaning agent preparation comprising proteases, such as subtilisins, with specific amino acid substitutions, is developed to maintain cleaning effectiveness under varying dishwasher temperatures, allowing for automatic dosing and reducing the need for frequent rinsing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of stationary object

If conventional cleaning agents are used in automatic dishwashers, then the cleaning agents can be stored for multiple dosing cycles, but the cleaning performance deteriorates on stubborn dried-on food residues when there are several days between wash cycles

Engineering Contradiction:
Improvestorage duration for multiple dosing cyclesVSAvoidcleaning performance on dried-on residues
Core Design Contradiction:
Duration of action of stationary objectVSReliability

Solution Approach 1:

The patent modifies the molecular structure of the protease enzyme through specific amino acid substitutions (e.g., positions 212, 12, 43, 122, 127, 154, 156, 160, 211, or 222) to enhance its thermal stability and activity. This parameter change at the molecular level allows the enzyme to maintain effective cleaning performance on dried-on residues even after prolonged storage in the dishwasher over multiple days between wash cycles.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If cleaning agents are formulated for high cleaning performance on tough residues, then the cleaning effectiveness improves, but the agents become more sensitive to temperature variations in the dishwasher

Engineering Contradiction:
Improvecleaning effectiveness on tough residuesVSAvoidtemperature sensitivity
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent introduces specific amino acid substitutions at defined positions in the protease sequence to fundamentally alter the enzyme's thermal stability parameters. These molecular modifications enable the cleaning agent to maintain high effectiveness on tough residues like dried-on minced meat and egg yolk while simultaneously resisting deactivation from temperature fluctuations during dishwasher cycles, including prolonged loading times.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If frequent rinsing is performed to remove stubborn residues, then the cleaning completeness improves, but the water consumption and time required increase

Engineering Contradiction:
Improvecleaning completenessVSAvoidwater consumption
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The patent employs a pre-modified protease enzyme with enhanced stability and activity that works effectively during the initial wash cycle even when dishes have been standing for several days. This preliminary action by the optimized enzyme breaks down stubborn dried-on residues during the first wash, eliminating the need for frequent additional rinsing cycles and thereby reducing water consumption and time requirements.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The protease-enhanced cleaning agent maintains high cleaning performance on tough residues, reducing the frequency of wash cycles and conserving water, while being phosphate-free for environmental friendliness.

Implementation Method 1

comprises at least one protease, preferably a protease derived from subtilisin

Methodology Applied
Scientific EffectEnzyme catalysis: Enzyme

Implementation Method 2

protease-enhanced cleaning agent maintains high cleaning performance on tough residues

Methodology Applied
Scientific EffectHydrolysis: Hydrolysis

Data Source

PatentUS12516272B2Cleaning agent comprising protease for automatic dosing
Publication Date: 2026.01.06 HENKEL KGAA

AI summary

A liquid cleaning agent composition may include at least one suitable protease and water in an amount of at least 30 wt. % and less, preferably 25 wt. % and less, in particular 15 wt. % or less based on the total composition.