Photosensitive Protein Memory Cell Chromophore Conversion
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Solution Overview
Problem
Existing protein-based memory technologies face challenges in improving the performance and stability of writing/reading operations due to low conversion rates between on and off states, which affects the signal-to-noise ratio and overall data readout efficiency.
Innovation Solution
A protein memory cell design incorporating first and second electrodes on a micro channel with a gap region and an outer region, utilizing photosensitive proteins like GFP mutants (e.g., GFP-F64L) that change conductivity based on structural conversion of the chromophore, allowing for high conversion rates between logical states upon light irradiation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If photosensitive proteins are used in protein-based memory technology, then biocompatibility and low heat generation are improved, but conversion rate between on and off states deteriorates
Solution Approach 1:
The patent modifies the amino acid sequence of GFP by substituting phenylalanine at position 64 with leucine, isoleucine, or valine. This parameter change in the protein structure fundamentally alters the photoisomerization properties of the chromophore, enabling high conversion rates (exceeding 99%) while maintaining the biocompatibility of the photosensitive protein.
2Temperature
If photosensitive proteins are used in protein-based memory technology, then low heat generation is improved, but signal-to-noise ratio deteriorates
Solution Approach 1:
By changing the amino acid at position 64 from phenylalanine to leucine, isoleucine, or valine, the patent achieves a conversion rate exceeding 99%, which directly improves the signal-to-noise ratio. This parameter change in the protein sequence optimizes the photosensitive protein's performance for high-precision data readout while maintaining low heat generation characteristics.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The high conversion rate of 99% between on and off states significantly improves the signal-to-noise ratio and stability of the writing/reading operations, enhancing the performance and reliability of the protein memory cell.
Implementation Method 1
a photosensitive protein changing conductivity between the first and second electrodes while moving between the gap region and the outer region depending on structural conversion of a chromophore
Implementation Method 2
a photosensitive protein changing conductivity between the first and second electrodes while moving between the gap region and the outer region depending on structural conversion of a chromophore
Data Source
AI summary
A protein memory cell and a protein memory system are provided. The protein memory cell includes: first and second electrodes disposed to be spaced apart from each other on a micro channel; a gap region defined between the first and second electrodes on the micro channel; an outer region defined as an opposite side to the gap region based on the first or second electrode on the micro channel; and a photosensitive protein changing conductivity between the first and second electrodes while moving between the gap region and the outer region depending on structural conversion of a chromophore.