Proton Beam Intensity Control via Betatron Oscillation Feedback
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Solution Overview
Problem
There is a need for efficient delivery of charged particles to tumors in cancer therapy, requiring precise correlation of charged particle beam intensity with delivery efficiency to minimize damage to healthy tissue, while ensuring uniform radiation dosage and precise tumor treatment.
Innovation Solution
A method and apparatus that utilize a raster beam scanning system in conjunction with multi-field charged particle cancer therapy, timed to patient respiration, incorporating a synchrotron with advanced ion beam control and targeting methods to optimize charged particle beam intensity and energy delivery, including a negative ion beam source and focusing systems for precise tumor treatment.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If charged particle beam intensity is increased to improve tumor treatment efficacy, then radiation delivery efficiency to tumor is improved, but damage to surrounding healthy tissue increases
Solution Approach 1:
The patent divides the radiation delivery process into multiple discrete fields (first field, second field, third field) that can be independently controlled. Each field can be targeted to specific spatial regions, allowing the system to deliver high intensity radiation to the tumor while segmenting and controlling exposure to surrounding healthy tissue. This segmentation enables selective intensity modulation across different spatial zones.
Solution Approach 2:
The patent implements local quality by varying the charged particle beam intensity and spatial distribution across different fields. The first field has different intensity and spatial characteristics compared to the second and third fields, allowing each region to receive optimized radiation parameters tailored to its specific requirements (tumor vs. healthy tissue), thereby achieving high delivery efficiency where needed while minimizing harm elsewhere.
2Manufacturing precision
If multi-field charged particle therapy is used to improve uniformity of radiation dosage, then treatment precision is improved, but system complexity increases
Solution Approach 1:
The system segments the radiation delivery into multiple independent fields (first field, second field, third field), each capable of being controlled separately. This segmentation allows precise control over the spatial distribution and intensity of each field, enabling uniform total dosage accumulation across the tumor volume while maintaining manageable complexity through modular field control.
Solution Approach 2:
The patent introduces spatial dimensionality by defining multiple fields with different spatial locations and characteristics. The first field, second field, and third field are positioned and oriented to cover different regions, adding a spatial dimension to the radiation delivery control. This dimensional approach enables precise three-dimensional dosage distribution while organizing complexity through structured spatial arrangement.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables efficient, accurate, and precise delivery of radiation to tumors with minimal damage to surrounding healthy tissue by correlating charged particle beam intensity with delivery efficiency and coordinating treatment with patient positioning and respiration, enhancing treatment efficacy and reducing tissue damage.
Implementation Method 1
a synchrotron with advanced ion beam control and targeting methods to optimize charged particle beam intensity and energy delivery
Implementation Method 2
incorporating a synchrotron with advanced ion beam control and targeting methods
Implementation Method 3
focusing systems for precise tumor treatment
Implementation Method 4
A method and apparatus that utilize a raster beam scanning system in conjunction with multi-field charged particle cancer therapy
Implementation Method 5
These particles damage the DNA of cells, ultimately causing their death
Implementation Method 6
Proton therapy works by aiming energetic ionizing particles, such as protons accelerated with a particle accelerator, onto a target tumor
Data Source
AI summary
The invention relates to treatment of solid cancers and more particularly to a method and apparatus correlating proton beam intensity with proton delivery efficiency, optionally in a raster beam scanning system. The system induces betatron oscillation on the proton beam causing the beam to traverse an extraction material resulting in slowed protons and a feedback current proportional to the proton flux. A controller receives the desired intensity from an irradiation plan and the feedback current and adjusts the radio-frequency field in the radio-frequency cavity system to yield an intensity of the proton beam that matches the desired intensity from the irradiation plan. Preferably, the intensity of the proton beam correlates with radiation delivery efficiency. The system preferably operates in conjunction with a multi-field charged particle cancer therapy system, with charged particle beam injection, particle beam acceleration, multi-axis charged particle beam control, and/or targeting methods and apparatus.