Loading Collapsible Pulmonary Implants onto Catheters

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Solution Overview

Problem

Existing devices face challenges in accurately and safely loading collapsible pulmonary implants onto delivery catheters without damaging them, and there is a need for a system that maintains the implant in its native state until use to prevent functional loss during storage and shipping.

Innovation Solution

A loading device comprising an outer and inner tubular structure with a narrowing passage that compresses the implant as it is slid into the catheter, along with optional features like a grasper and shape-memory materials to stabilize and release the implant, ensuring easy and secure loading.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Length of moving object

If the implant is compressed for delivery through small body pathways, then the implant can be delivered through the catheter, but the implant may lose functionality or get damaged during compression and storage

Engineering Contradiction:
Improveimplant diameterVSAvoidimplant functionality
Core Design Contradiction:
Length of moving objectVSReliability

Solution Approach 1:

The implant is nested within a protective housing structure that maintains it in an uncollapsed state during storage and shipping. The housing acts as a container that preserves the implant's native configuration, preventing damage while allowing compact delivery when needed.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The implant is pre-loaded into the housing structure in its uncollapsed state before storage or shipping. This preliminary loading action ensures the implant maintains its functional configuration throughout storage, and the housing is designed to facilitate easy loading without requiring compression of the implant itself.

Inventive Principle:
Principle #10Preliminary action

2Ease of operation

If the implant is pre-loaded onto the catheter, then delivery is simplified, but the implant may degrade or lose functionality during extended storage on the shelf

Engineering Contradiction:
Improveloading simplicityVSAvoidimplant functionality during storage
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The system is segmented into two separate components: the implant stored independently in a protective housing, and the delivery catheter. This segmentation allows the implant to remain in its optimal uncollapsed state during storage while the catheter remains ready for delivery, combining the benefits of pre-prepared delivery with preservation of implant functionality.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The housing structure serves as an intermediary between the implant and the delivery catheter. It protects the implant during storage and provides a controlled interface for loading the implant onto the catheter only when needed, preventing premature degradation while enabling easy loading.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Manufacturing precision

If a loading device is used to load the implant onto the catheter, then accurate and damage-free loading is achieved, but the device complexity increases

Engineering Contradiction:
Improveloading accuracyVSAvoidloading device structure
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The housing structure utilizes a flexible or compliant material that can deform to accommodate the implant during loading, then return to its original shape to secure the implant. This flexibility simplifies the loading mechanism compared to rigid structures, reducing overall device complexity while maintaining precise control over the implant positioning.

Inventive Principle:
Principle #30Flexible shells and thin films

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device allows for simple, accurate, and predictable loading of collapsible implants onto catheters, preventing damage and functional degradation, while maintaining the implant in its uncollapsed state until use, ensuring correct orientation and ease of use.

Implementation Method 1

shape-memory materials to stabilize and release the implant

Methodology Applied
Scientific EffectShape memory: Shape Memory Alloy

Data Source

PatentEP2120821B1Loading a device for a pulmonary implant
Publication Date: 2020.05.27 PULMONX CORP
  • EP2120821B1 patent drawingFigure 1a
  • EP2120821B1 patent drawingFigure 1b
  • EP2120821B1 patent drawingFigure 1c

AI summary

Devices for loading a collapsible implant onto a delivery catheter. In one aspect, a loading device compnses an outer tubular structure and an inner tubular structure. The outer tubular structure compnses a narrowing passage configured to receive a catheter at one end and a collapsible implant at another end. The inner tubular structure is configured to move slidably and co-axially within the outer tubular structure. The inner tubular structure comprises a earner pin configured to move within the narrowing passage as the inner tubular structure slides into the outer tubular structure. The sliding of the inner tubular structure into the outer tubular structure causes an implant mounted on the earner pin to collapse as the implant moves through the narrowing passage and into the distal end of a catheter. In another aspect, the outer tubular structure further comprises a grasper to stabilize the catheter for receipt of the collapsible implant.