Pulse Protein Solubility at Acid pH via Calcium Extraction

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Solution Overview

Problem

Existing methods for producing protein solutions from pulses face challenges in achieving high protein content, solubility, and heat stability at acid pH values, often requiring stabilizers and resulting in off-flavors or precipitation issues.

Innovation Solution

A method involving the extraction of pulse proteins using an aqueous calcium chloride solution, followed by pH adjustment to 1.5-4.4, clarification, concentration, and diafiltration to produce a pulse protein product with a protein content of at least 90 wt% (N×6.25) d.b., which is completely soluble and heat stable at acid pH values.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If conventional methods are used to produce pulse protein solutions, then protein content can be increased, but solubility and heat stability at acid pH values deteriorate, requiring stabilizers and causing off-flavors or precipitation

Engineering Contradiction:
Improveprotein contentVSAvoidsolubility and heat stability at acid pH
Core Design Contradiction:
Quantity of substanceVSReliability

Solution Approach 1:

The patent applies parameter changes by adjusting pH to 1.5-4.4 during processing, using calcium chloride extraction, and controlling ionic strength during concentration to achieve both high protein content (≥90 wt%) and excellent solubility with heat stability at acid pH values without requiring stabilizers

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses calcium chloride as an intermediary substance during extraction to solubilize pulse proteins, and employs selective membrane techniques as intermediaries for concentration while maintaining ionic strength, resulting in protein products that are completely soluble and heat stable at acid pH

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If pulse protein solutions are concentrated to high protein content, then productivity increases, but precipitation issues arise at acid pH values

Engineering Contradiction:
Improveprotein concentration efficiencyVSAvoidprecipitation at acid pH
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent changes parameters by maintaining specific ionic strength during concentration and adjusting pH to 1.5-4.4, enabling concentration to high protein content (≥90 wt%) without precipitation, as the controlled ionic environment prevents protein aggregation

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs selective membrane techniques as intermediaries for concentration that maintain ionic strength, preventing precipitation while achieving high protein content efficiently

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If stabilizers are added to maintain solubility, then solubility improves, but off-flavors are generated

Engineering Contradiction:
Improvesolubility maintenanceVSAvoidoff-flavors
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent applies self-service by producing protein products through calcium chloride extraction and pH adjustment that are inherently stable and completely soluble at acid pH without requiring any stabilizers, thus avoiding off-flavors entirely

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent changes the chemical environment by adjusting pH to 1.5-4.4 and controlling ionic strength, creating conditions where the protein itself maintains solubility without stabilizers, eliminating off-flavor generation

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method results in pulse protein products that are highly soluble, heat stable, and low in phytic acid, suitable for protein fortification in beverages without precipitation, with a clean flavor and no off-odors, and can be used in various applications including food, nutritional supplements, and industrial products.

Implementation Method 1

extracting a pulse protein source with an aqueous calcium salt solution, preferably an aqueous calcium chloride solution, to cause solubilization of pulse protein from the protein source

Methodology Applied
Scientific EffectSolubilization: Solvation

Implementation Method 2

adjusting the pH of the aqueous pulse protein solution to a pH of about 1.5 to about 4.4, preferably about 2 to about 4, to produce an acidified pulse protein solution

Methodology Applied
Scientific EffectpH adjustment:

Implementation Method 3

optionally concentrating the aqueous pulse protein solution while maintaining the ionic strength substantially constant by a selective membrane technique

Methodology Applied
Scientific EffectSelective membrane separation: Semipermeable Membrane

Implementation Method 4

optionally diafiltering the concentrated pulse protein solution

Methodology Applied
Scientific EffectDiafiltration:

Data Source

PatentUS10506821B2Production of soluble protein solutions from pulses
Publication Date: 2019.12.17 BURCON MUTRASCI MB CORP

AI summary

A pulse protein product, which may be an isolate, produces heat-stable solutions at low pH values and is useful for the fortification of acidic beverages such as soft drinks and sports drinks without precipitation of protein. The pulse protein product is obtained by extracting a pulse protein source material with an aqueous calcium salt solution to form an aqueous pulse protein solution, separating the aqueous pulse protein solution from residual pulse protein source, adjusting the pH of the aqueous pulse protein solution to a pH of about 1.5 to about 4.4 to produce an acidified pulse protein solution, which may be dried, following optional concentration and diafiltration, to provide the pulse protein product.